"Immunological Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The interfaces between T-CELLS and ANTIGEN-PRESENTING CELLS. Supramolecular organization of proteins takes place at these synapses involving various types of immune cells. Immunological synapses can have several functions including LYMPHOCYTE ACTIVATION; enhancing, balancing, or terminating signaling; or directing cytokine secretion.
Descriptor ID |
D054992
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MeSH Number(s) |
A11.284.149.165.420.548 A15.382.370
|
Concept/Terms |
Immunological Synapses- Immunological Synapses
- Immunological Synapse
- Synapse, Immunological
- Synapses, Immunological
|
Below are MeSH descriptors whose meaning is more general than "Immunological Synapses".
Below are MeSH descriptors whose meaning is more specific than "Immunological Synapses".
This graph shows the total number of publications written about "Immunological Synapses" by people in this website by year, and whether "Immunological Synapses" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunological Synapses" by people in Profiles.
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Grier JT, Forbes LR, Monaco-Shawver L, Oshinsky J, Atkinson TP, Moody C, Pandey R, Campbell KS, Orange JS. Human immunodeficiency-causing mutation defines CD16 in spontaneous NK cell cytotoxicity. J Clin Invest. 2012 Oct; 122(10):3769-80.
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Rosental B, Brusilovsky M, Hadad U, Oz D, Appel MY, Afergan F, Yossef R, Rosenberg LA, Aharoni A, Cerwenka A, Campbell KS, Braiman A, Porgador A. Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44. J Immunol. 2011 Dec 01; 187(11):5693-702.
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Beal AM, Anikeeva N, Varma R, Cameron TO, Vasiliver-Shamis G, Norris PJ, Dustin ML, Sykulev Y. Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain. Immunity. 2009 Oct 16; 31(4):632-42.
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Beal AM, Anikeeva N, Varma R, Cameron TO, Norris PJ, Dustin ML, Sykulev Y. Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL. J Immunol. 2008 Oct 1; 181(7):4815-24.