Gene Knockdown Techniques

"Gene Knockdown Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.

Descriptor ID	D055785
MeSH Number(s)	E05.393.335.500
Concept/Terms	Gene Knockdown Techniques Gene Knockdown Techniques Gene Knockdown Technique Knockdown Technique, Gene Knockdown Techniques, Gene Technique, Gene Knockdown Techniques, Gene Knockdown Gene Knockdown Gene Knockdowns Knockdown, Gene Knockdowns, Gene Gene Knock-Down Gene Knock-Downs Knock-Down, Gene Knock-Downs, Gene Gene Knock-Down Techniques Gene Knock-Down Technique Knock-Down Technique, Gene Knock-Down Techniques, Gene Technique, Gene Knock-Down Techniques, Gene Knock-Down Gene Knock Down Gene Knock Downs Knock Down, Gene Knock Downs, Gene Gene Knock Down Techniques

Below are MeSH descriptors whose meaning is more general than "Gene Knockdown Techniques".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Gene Targeting [E05.393.335]
Gene Knockdown Techniques [E05.393.335.500]

Below are MeSH descriptors whose meaning is related to "Gene Knockdown Techniques".

Below are MeSH descriptors whose meaning is more specific than "Gene Knockdown Techniques".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Gene Knockdown Techniques" by people in this website by year, and whether "Gene Knockdown Techniques" was a major or minor topic of these publications.

Bar chart showing 79 publications over 14 distinct years, with a maximum of 12 publications in 2009

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2008	1	1
2009	12	12
2010	9	9
2011	11	11
2012	7	7
2013	11	11
2014	3	3
2015	3	3
2016	2	2
2017	8	8
2018	1	1
2019	2	2
2020	7	7
2021	2	2

Below are the most recent publications written about "Gene Knockdown Techniques" by people in Profiles.

Darga EP, Dolce EM, Fang F, Kidwell KM, Gersch CL, Kregel S, Thomas DG, Gill A, Brown ME, Gross S, Connelly M, Holinstat M, Cobain EF, Rae JM, Hayes DF, Paoletti C. PD-L1 expression on circulating tumor cells and platelets in patients with metastatic breast cancer. PLoS One. 2021; 16(11):e0260124.

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Lu Z, Ortiz A, Verginadis II, Peck AR, Zahedi F, Cho C, Yu P, DeRita RM, Zhang H, Kubanoff R, Sun Y, Yaspan AT, Krespan E, Beiting DP, Radaelli E, Ryeom SW, Diehl JA, Rui H, Koumenis C, Fuchs SY. Regulation of intercellular biomolecule transfer-driven tumor angiogenesis and responses to anticancer therapies. J Clin Invest. 2021 05 17; 131(10).

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Sanders SS, Hernandez LM, Soh H, Karnam S, Walikonis RS, Tzingounis AV, Thomas GM. The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment. Elife. 2020 11 13; 9.

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Layer JV, Debaize L, Van Scoyk A, House NC, Brown AJ, Liu Y, Stevenson KE, Hemann M, Roberts SA, Price BD, Weinstock DM, Day TA. Polymerase d promotes chromosomal rearrangements and imprecise double-strand break repair. Proc Natl Acad Sci U S A. 2020 11 03; 117(44):27566-27577.

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Elmadany N, Logiacco F, Buonfiglioli A, Haage VC, Wright-Jin EC, Schattenberg A, Papawassiliou RM, Kettenmann H, Semtner M, Gutmann DH. Neurofibromatosis 1 - Mutant microglia exhibit sexually-dimorphic cyclic AMP-dependent purinergic defects. Neurobiol Dis. 2020 10; 144:105030.

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Li F, Mladenov E, Mortoga S, Iliakis G. SCFSKP2 regulates APC/CCDH1-mediated degradation of CTIP to adjust DNA-end resection in G2-phase. Cell Death Dis. 2020 07 18; 11(7):548.

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Itskovich SS, Gurunathan A, Clark J, Burwinkel M, Wunderlich M, Berger MR, Kulkarni A, Chetal K, Venkatasubramanian M, Salomonis N, Kumar AR, Lee LH. MBNL1 regulates essential alternative RNA splicing patterns in MLL-rearranged leukemia. Nat Commun. 2020 05 12; 11(1):2369.

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Barbarino M, Cesari D, Bottaro M, Luzzi L, Namagerdi A, Bertolino FM, Bellan C, Proietti F, Somma P, Micheli M, de Santi MM, Guazzo R, Mutti L, Pirtoli L, Paladini P, Indovina P, Giordano A. PRMT5 silencing selectively affects MTAP-deleted mesothelioma: In vitro evidence of a novel promising approach. J Cell Mol Med. 2020 05; 24(10):5565-5577.

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Gao Y, Yan Y, Tripathi S, Pentinmikko N, Amaral A, Päivinen P, Domènech-Moreno E, Andersson S, Wong IPL, Clevers H, Katajisto P, Mäkelä TP. LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate. Gastroenterology. 2020 04; 158(5):1389-1401.e10.

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Richter C, Marquardt S, Li F, Spitschak A, Murr N, Edelh?user BAH, Iliakis G, P?tzer BM, Logotheti S. Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness. J Exp Clin Cancer Res. 2019 Jul 08; 38(1):292.

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