Gene Knockout Techniques

"Gene Knockout Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Techniques to alter a gene sequence that result in an inactivated gene, or one in which the expression can be inactivated at a chosen time during development to study the loss of function of a gene.

Descriptor ID	D055786
MeSH Number(s)	E05.393.335.750
Concept/Terms	Gene Knockout Techniques Gene Knockout Techniques Gene Knockout Technique Knockout Technique, Gene Knockout Techniques, Gene Technique, Gene Knockout Techniques, Gene Knockout Gene Knockout Gene Knockouts Knockout, Gene Knockouts, Gene Gene Knock-Out Techniques Gene Knock-Out Technique Knock-Out Technique, Gene Knock-Out Techniques, Gene Technique, Gene Knock-Out Techniques, Gene Knock-Out Gene Knock Out Gene Knock Outs Knock Out, Gene Knock Outs, Gene Out, Gene Knock Outs, Gene Knock Gene Knock Out Techniques

Below are MeSH descriptors whose meaning is more general than "Gene Knockout Techniques".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Gene Targeting [E05.393.335]
Gene Knockout Techniques [E05.393.335.750]

Below are MeSH descriptors whose meaning is related to "Gene Knockout Techniques".

Below are MeSH descriptors whose meaning is more specific than "Gene Knockout Techniques".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Gene Knockout Techniques" by people in this website by year, and whether "Gene Knockout Techniques" was a major or minor topic of these publications.

Bar chart showing 52 publications over 15 distinct years, with a maximum of 9 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	0	1	1
2010	0	2	2
2011	1	8	9
2012	1	2	3
2013	0	3	3
2014	0	1	1
2015	0	4	4
2016	1	3	4
2017	1	6	7
2018	1	3	4
2019	0	6	6
2020	0	2	2
2021	0	4	4
2022	1	0	1
2024	0	1	1

Below are the most recent publications written about "Gene Knockout Techniques" by people in Profiles.

Sehgal A, Milman T, Li Q, Pulido JS. Histological Findings in the Eyes of Abcc6 Knockout Rat Model of Pseudoxanthoma Elasticum. Transl Vis Sci Technol. 2024 04 02; 13(4):29.

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Stefanski HE, Xing Y, Nicholls J, Jonart L, Goren E, Taylor PA, Mills AA, Riddle M, McGrath J, Tolar J, Hollander GA, Blazar BR. P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss. PLoS One. 2022; 17(1):e0261770.

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Ippolito M, De Pascali F, Inoue A, Benovic JL. Phenylalanine 193 in Extracellular Loop 2 of the ?2-Adrenergic Receptor Coordinates ?-Arrestin Interaction. Mol Pharmacol. 2022 02; 101(2):87-94.

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Young MP, Schug ZT, Booth DM, Yule DI, Mikoshiba K, Hajn?czky G, Joseph SK. Metabolic adaptation to the chronic loss of Ca2+ signaling induced by KO of IP3 receptors or the mitochondrial Ca2+?uniporter. J Biol Chem. 2022 01; 298(1):101436.

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Karthikeyan S, Waters IG, Dennison L, Chu D, Donaldson J, Shin DH, Rosen DM, Gonzalez-Ericsson PI, Sanchez V, Sanders ME, Pantone MV, Bergman RE, Davidson BA, Reed SC, Zabransky DJ, Cravero K, Kyker-Snowman K, Button B, Wong HY, Hurley PJ, Croessmann S, Park BH. Hierarchical tumor heterogeneity mediated by cell contact between distinct genetic subclones. J Clin Invest. 2021 03 15; 131(6).

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Schneider M, Pawlak R, Weber GR, Dillinger AE, Kuespert S, Iozzo RV, Quigley HA, Ohlmann A, Tamm ER, Fuchshofer R. A novel ocular function for decorin in the aqueous humor outflow. Matrix Biol. 2021 03; 97:1-19.

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Buraschi S, Neill T, Xu SQ, Palladino C, Belfiore A, Iozzo RV, Morrione A. Progranulin/EphA2 axis: A novel oncogenic mechanism in bladder cancer. Matrix Biol. 2020 11; 93:10-24.

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Fong LY, Taccioli C, Palamarchuk A, Tagliazucchi GM, Jing R, Smalley KJ, Fan S, Altemus J, Fiehn O, Huebner K, Farber JL, Croce CM. Abrogation of esophageal carcinoma development in miR-31 knockout rats. Proc Natl Acad Sci U S A. 2020 03 17; 117(11):6075-6085.

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Cai W, Su L, Liao L, Liu ZZ, Langbein L, Dulaimi E, Testa JR, Uzzo RG, Zhong Z, Jiang W, Yan Q, Zhang Q, Yang H. PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth. Nat Commun. 2019 12 20; 10(1):5800.

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Pellicani R, Poletto E, Andreuzzi E, Paulitti A, Doliana R, Bizzotto D, Braghetta P, Colladel R, Tarticchio G, Sabatelli P, Bucciotti F, Bressan G, Iozzo RV, Colombatti A, Bonaldo P, Mongiat M. Multimerin-2 maintains vascular stability and permeability. Matrix Biol. 2020 05; 87:11-25.

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