"Cathepsin L" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously-expressed cysteine protease that plays an enzymatic role in POST-TRANSLATIONAL PROTEIN PROCESSING of proteins within SECRETORY GRANULES.
| Descriptor ID |
D056668
|
| MeSH Number(s) |
D08.811.277.656.224.407 D08.811.277.656.262.500.157 D08.811.277.656.300.200.157
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cathepsin L".
Below are MeSH descriptors whose meaning is more specific than "Cathepsin L".
This graph shows the total number of publications written about "Cathepsin L" by people in this website by year, and whether "Cathepsin L" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cathepsin L" by people in Profiles.
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Mady LJ, Ajibade DV, Hsaio C, Teichert A, Fong C, Wang Y, Christakos S, Bikle DD. The Transient Role for Calcium and Vitamin D during the Developmental Hair Follicle Cycle. J Invest Dermatol. 2016 07; 136(7):1337-1345.
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Cartledge DM, Colella R, Glazewski L, Lu G, Mason RW. Inhibitors of cathepsins B and L induce autophagy and cell death in neuroblastoma cells. Invest New Drugs. 2013 Feb; 31(1):20-9.
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Colella R, Lu G, Glazewski L, Korant B, Matlapudi A, England MR, Craft C, Frantz CN, Mason RW. Induction of cell death in neuroblastoma by inhibition of cathepsins B and L. Cancer Lett. 2010 Aug 28; 294(2):195-203.
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Rebbaa A, Chu F, Sudha T, Gallati C, Dier U, Dyskin E, Yalcin M, Bianchini C, Shaker O, Mousa SA. The anti-angiogenic activity of NSITC, a specific cathepsin L inhibitor. Anticancer Res. 2009 Nov; 29(11):4473-81.
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Zheng X, Chu F, Chou PM, Gallati C, Dier U, Mirkin BL, Mousa SA, Rebbaa A. Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism. Am J Physiol Cell Physiol. 2009 Jan; 296(1):C65-74.
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Cailhier JF, Sirois I, Laplante P, Lepage S, Raymond MA, Brassard N, Prat A, Iozzo RV, Pshezhetsky AV, Hébert MJ. Caspase-3 activation triggers extracellular cathepsin L release and endorepellin proteolysis. J Biol Chem. 2008 Oct 3; 283(40):27220-9.
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Qiu Z, Hingley ST, Simmons G, Yu C, Das Sarma J, Bates P, Weiss SR. Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry. J Virol. 2006 Jun; 80(12):5768-76.
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Sol-Church K, Picerno GN, Stabley DL, Frenck J, Xing S, Bertenshaw GP, Mason RW. Evolution of placentally expressed cathepsins. Biochem Biophys Res Commun. 2002 Apr 26; 293(1):23-9.