"Lac Repressors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bacterial repressor proteins that bind to the LAC OPERON and thereby prevent the synthesis of proteins involved in catabolism of LACTOSE. When lactose levels are high lac repressors undergo an allosteric change that causes their release from the DNA and the resumption of lac operon transcription.
Descriptor ID |
D056968
|
MeSH Number(s) |
D12.776.097.521 D12.776.260.703.600 D12.776.930.780.781
|
Concept/Terms |
Lac Repressors- Lac Repressors
- Repressors, Lac
- LacI Proteins
- Proteins, LacI
- Lac Repressor
- Repressor, Lac
|
Below are MeSH descriptors whose meaning is more general than "Lac Repressors".
Below are MeSH descriptors whose meaning is more specific than "Lac Repressors".
This graph shows the total number of publications written about "Lac Repressors" by people in this website by year, and whether "Lac Repressors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2002 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Lac Repressors" by people in Profiles.
-
Goodson KA, Wang Z, Haeusler AR, Kahn JD, English DS. LacI-DNA-IPTG loops: equilibria among conformations by single-molecule FRET. J Phys Chem B. 2013 Apr 25; 117(16):4713-22.
-
Haeusler AR, Goodson KA, Lillian TD, Wang X, Goyal S, Perkins NC, Kahn JD. FRET studies of a landscape of Lac repressor-mediated DNA loops. Nucleic Acids Res. 2012 May; 40(10):4432-45.
-
Fried MG, Stickle DF, Smirnakis KV, Adams C, MacDonald D, Lu P. Role of hydration in the binding of lac repressor to DNA. J Biol Chem. 2002 Dec 27; 277(52):50676-82.