"Cell Cycle Checkpoints" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and without mistakes, all the processes required to replicate the GENOME and CYTOPLASM, and divide them equally between two daughter cells. If cells sense they have not completed these processes or that the environment does not have the nutrients and growth hormones in place to proceed, then the cells are restrained (or "arrested") until the processes are completed and growth conditions are suitable.
Descriptor ID |
D059447
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MeSH Number(s) |
G04.144.109
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Concept/Terms |
Cell Cycle Checkpoints- Cell Cycle Checkpoints
- Cell Cycle Checkpoint
- Checkpoint, Cell Cycle
- Checkpoints, Cell Cycle
Cell Cycle Transition Points- Cell Cycle Transition Points
- Cell Cycle-Transition Points
- Cell Cycle-Transition Point
- Cycle-Transition Point, Cell
- Point, Cell Cycle-Transition
Cell Cycle Arrest- Cell Cycle Arrest
- Arrest, Cell Cycle
- Arrests, Cell Cycle
- Cell Cycle Arrests
Cell Cycle Control- Cell Cycle Control
- Cell Cycle Controls
- Control, Cell Cycle
- Controls, Cell Cycle
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Below are MeSH descriptors whose meaning is more general than "Cell Cycle Checkpoints".
Below are MeSH descriptors whose meaning is more specific than "Cell Cycle Checkpoints".
This graph shows the total number of publications written about "Cell Cycle Checkpoints" by people in this website by year, and whether "Cell Cycle Checkpoints" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2012 | 0 | 3 | 3 |
2013 | 1 | 1 | 2 |
2014 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2017 | 2 | 4 | 6 |
2018 | 1 | 2 | 3 |
2020 | 1 | 1 | 2 |
2021 | 0 | 4 | 4 |
2022 | 1 | 2 | 3 |
2023 | 0 | 1 | 1 |
2024 | 1 | 1 | 2 |
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click here.
Below are the most recent publications written about "Cell Cycle Checkpoints" by people in Profiles.
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Andretta E, Costa A, Ventura E, Quintiliani M, Damiano S, Giordano A, Morrione A, Ciarcia R. Capsaicin Exerts Antitumor Activity in Mesothelioma Cells. Nutrients. 2024 Nov 01; 16(21).
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Desai V, Tadinada SM, Shaghaghi H, Summer R, Lai JCK, Bhushan A. Combination Treatment of Biochanin A and Atorvastatin Alters Mitochondrial Bioenergetics, Modulating Cell Metabolism and Inducing Cell Cycle Arrest in Pancreatic Cancer Cells. Anticancer Res. 2024 Jun; 44(6):2307-2323.
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Li F, Mladenov E, Sun Y, Soni A, Stuschke M, Timmermann B, Iliakis G. Low CDK Activity and Enhanced Degradation by APC/CCDH1 Abolishes CtIP Activity and Alt-EJ in Quiescent Cells. Cells. 2023 Jun 01; 12(11).
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Kumar S, Mulchandani V, Das Sarma J. Methanolic neem (Azadirachta indica) stem bark extract induces cell cycle arrest, apoptosis and inhibits the migration of cervical cancer cells in vitro. BMC Complement Med Ther. 2022 Sep 10; 22(1):239.
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Scalia P, Williams SJ, Fujita-Yamaguchi Y, Giordano A. Cell cycle control by the insulin-like growth factor signal: at the crossroad between cell growth and mitotic regulation. Cell Cycle. 2023 01; 22(1):1-37.
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Chandramouly G. Gadd45 in DNA Demethylation and DNA Repair. Adv Exp Med Biol. 2022; 1360:55-67.
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Srour AM, Panda SS, Mostafa A, Fayad W, El-Manawaty MA, A F Soliman A, Moatasim Y, El Taweel A, Abdelhameed MF, Bekheit MS, Ali MA, Girgis AS. Synthesis of aspirin-curcumin mimic conjugates of potential antitumor and anti-SARS-CoV-2 properties. Bioorg Chem. 2021 12; 117:105466.
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Alam A, Jamil AK, Van Zyl JS, Medel-Martinez H, Bottiglieri T, Wasek B, Felius J, Lima B, Hall SA, Joseph SM. Urinary Cell-Cycle Arrest Biomarkers as Early Predictors of Acute Kidney Injury After Ventricular Assist Device Implantation or Cardiac Transplantation. J Cardiothorac Vasc Anesth. 2022 08; 36(8 Pt A):2303-2312.
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Krieger LM, Mladenov E, Soni A, Demond M, Stuschke M, Iliakis G. Disruption of Chromatin Dynamics by Hypotonic Stress Suppresses HR and Shifts DSB Processing to Error-Prone SSA. Int J Mol Sci. 2021 Oct 11; 22(20).
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Farkas M, Hashimoto H, Bi Y, Davuluri RV, Resnick-Silverman L, Manfredi JJ, Debler EW, McMahon SB. Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates. Nat Commun. 2021 01 20; 12(1):484.