Alcohol Dehydrogenase

"Alcohol Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A zinc-containing enzyme which oxidizes primary and secondary alcohols or hemiacetals in the presence of NAD. In alcoholic fermentation, it catalyzes the final step of reducing an aldehyde to an alcohol in the presence of NADH and hydrogen.

Descriptor ID	D000426
MeSH Number(s)	D08.811.682.047.820.250
Concept/Terms	Alcohol Dehydrogenase Alcohol Dehydrogenase Dehydrogenase, Alcohol Alcohol-NAD+ Oxidoreductase Alcohol NAD+ Oxidoreductase Oxidoreductase, Alcohol-NAD+ Alcohol Dehydrogenase (NAD+) Alcohol Dehydrogenase II Alcohol Dehydrogenase II Yeast Alcohol Dehydrogenase Yeast Alcohol Dehydrogenase Alcohol Dehydrogenase, Yeast Dehydrogenase, Yeast Alcohol Alcohol Dehydrogenase I Alcohol Dehydrogenase I

Below are MeSH descriptors whose meaning is more general than "Alcohol Dehydrogenase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Oxidoreductases [D08.811.682]
Alcohol Oxidoreductases [D08.811.682.047]
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases [D08.811.682.047.820]
Alcohol Dehydrogenase [D08.811.682.047.820.250]

Below are MeSH descriptors whose meaning is related to "Alcohol Dehydrogenase".

Below are MeSH descriptors whose meaning is more specific than "Alcohol Dehydrogenase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Alcohol Dehydrogenase" by people in this website by year, and whether "Alcohol Dehydrogenase" was a major or minor topic of these publications.

Bar chart showing 17 publications over 13 distinct years, with a maximum of 3 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
2001	0	1	1
2002	0	1	1
2003	1	0	1
2004	1	0	1
2007	1	0	1
2008	0	1	1
2009	1	1	2
2011	2	1	3
2012	1	0	1
2013	1	1	2
2014	0	1	1
2024	0	1	1

Below are the most recent publications written about "Alcohol Dehydrogenase" by people in Profiles.

Flashner S, Shimonosono M, Tomita Y, Matsuura N, Ohashi S, Muto M, Klein-Szanto AJ, Alan Diehl J, Chen CH, Mochly-Rosen D, Weinberg KI, Nakagawa H. ALDH2 dysfunction and alcohol cooperate in cancer stem cell enrichment. Carcinogenesis. 2024 02 12; 45(1-2):95-106.

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Romero F, Shah D, Duong M, Stafstrom W, Hoek JB, Kallen CB, Lang CH, Summer R. Chronic alcohol ingestion in rats alters lung metabolism, promotes lipid accumulation, and impairs alveolar macrophage functions. Am J Respir Cell Mol Biol. 2014 Dec; 51(6):840-9.

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Roston D, Islam Z, Kohen A. Kinetic isotope effects as a probe of hydrogen transfers to and from common enzymatic cofactors. Arch Biochem Biophys. 2014 Feb 15; 544:96-104.

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Roston D, Islam Z, Kohen A. Isotope effects as probes for enzyme catalyzed hydrogen-transfer reactions. Molecules. 2013 May 14; 18(5):5543-67.

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Nagel ZD, Meadows CW, Dong M, Bahnson BJ, Klinman JP. Active site hydrophobic residues impact hydrogen tunneling differently in a thermophilic alcohol dehydrogenase at optimal versus nonoptimal temperatures. Biochemistry. 2012 May 22; 51(20):4147-56.

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Lee J, Jang YS, Choi SJ, Im JA, Song H, Cho JH, Seung do Y, Papoutsakis ET, Bennett GN, Lee SY. Metabolic engineering of Clostridium acetobutylicum ATCC 824 for isopropanol-butanol-ethanol fermentation. Appl Environ Microbiol. 2012 Mar; 78(5):1416-23.

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Karahanian E, Quintanilla ME, Tampier L, Rivera-Meza M, Bustamante D, Gonzalez-Lira V, Morales P, Herrera-Marschitz M, Israel Y. Ethanol as a prodrug: brain metabolism of ethanol mediates its reinforcing effects. Alcohol Clin Exp Res. 2011 Apr; 35(4):606-12.

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Israel Y, Rivera-Meza M, Quintanilla ME, Sapag A, Tampier L. Acetaldehyde burst protection of ADH1B*2 against alcoholism: an additional hormesis protection against esophageal cancers following alcohol consumption? Alcohol Clin Exp Res. 2011 May; 35(5):806-10.

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Lee JY, Jang YS, Lee J, Papoutsakis ET, Lee SY. Metabolic engineering of Clostridium acetobutylicum M5 for highly selective butanol production. Biotechnol J. 2009 Oct; 4(10):1432-40.

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Rivera-Meza M, Quintanilla ME, Tampier L, Mura CV, Sapag A, Israel Y. Mechanism of protection against alcoholism by an alcohol dehydrogenase polymorphism: development of an animal model. FASEB J. 2010 Jan; 24(1):266-74.

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