Alkylation

"Alkylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The covalent bonding of an alkyl group to an organic compound. It can occur by a simple addition reaction or by substitution of another functional group.

Descriptor ID	D000478
MeSH Number(s)	G02.111.035 G02.607.094 G03.059
Concept/Terms	Alkylation Alkylation Alkylations

Below are MeSH descriptors whose meaning is more general than "Alkylation".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Alkylation [G02.111.035]
Organic Chemistry Phenomena [G02.607]
Alkylation [G02.607.094]
Metabolism [G03]
Alkylation [G03.059]

Below are MeSH descriptors whose meaning is related to "Alkylation".

Below are MeSH descriptors whose meaning is more specific than "Alkylation".

Alkylation
Methylation

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Alkylation" by people in this website by year, and whether "Alkylation" was a major or minor topic of these publications.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 2003 and 2004 and 2005 and 2006 and 2008 and 2021

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2003	1	1
2004	1	1
2005	1	1
2006	1	1
2008	1	1
2021	1	1

Below are the most recent publications written about "Alkylation" by people in Profiles.

Bonilla B, Brown AJ, Hengel SR, Rapchak KS, Mitchell D, Pressimone CA, Fagunloye AA, Luong TT, Russell RA, Vyas RK, Mertz TM, Zaher HS, Mosammaparast N, Malc EP, Mieczkowski PA, Roberts SA, Bernstein KA. The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions. Elife. 2021 11 01; 10.

View in: PubMed
Morgan-Kiss RM, Chan LK, Modla S, Weber TS, Warner M, Czymmek KJ, Hanson TE. Chlorobaculum tepidum regulates chlorosome structure and function in response to temperature and electron donor availability. Photosynth Res. 2009 Jan; 99(1):11-21.

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Tomita K, Niida A, Oishi S, Ohno H, Cluzeau J, Navenot JM, Wang ZX, Peiper SC, Fujii N. Structure-activity relationship study on small peptidic GPR54 agonists. Bioorg Med Chem. 2006 Nov 15; 14(22):7595-603.

View in: PubMed
Yu BZ, Pan YH, Janssen MJ, Bahnson BJ, Jain MK. Kinetic and structural properties of disulfide engineered phospholipase A2: insight into the role of disulfide bonding patterns. Biochemistry. 2005 Mar 8; 44(9):3369-79.

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Regueiro-Ren A, Naidu BN, Zheng X, Hudyma TW, Connolly TP, Matiskella JD, Zhang Y, Kim OK, Sorenson ME, Pucci M, Clark J, Bronson JJ, Ueda Y. Novel semi-synthetic nocathiacin antibiotics: synthesis and antibacterial activity of bis- and mono-O-alkylated derivatives. Bioorg Med Chem Lett. 2004 Jan 5; 14(1):171-5.

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Chiou SJ, Riordan CG, Rheingold AL. Synthetic modeling of zinc thiolates: quantitative assessment of hydrogen bonding in modulating sulfur alkylation rates. Proc Natl Acad Sci U S A. 2003 Apr 1; 100(7):3695-700.

View in: PubMed

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