"Alkylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The covalent bonding of an alkyl group to an organic compound. It can occur by a simple addition reaction or by substitution of another functional group.
| Descriptor ID |
D000478
|
| MeSH Number(s) |
G02.111.035 G02.607.094 G03.059
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Alkylation".
Below are MeSH descriptors whose meaning is more specific than "Alkylation".
This graph shows the total number of publications written about "Alkylation" by people in this website by year, and whether "Alkylation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Alkylation" by people in Profiles.
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Morgan-Kiss RM, Chan LK, Modla S, Weber TS, Warner M, Czymmek KJ, Hanson TE. Chlorobaculum tepidum regulates chlorosome structure and function in response to temperature and electron donor availability. Photosynth Res. 2009 Jan; 99(1):11-21.
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Tomita K, Niida A, Oishi S, Ohno H, Cluzeau J, Navenot JM, Wang ZX, Peiper SC, Fujii N. Structure-activity relationship study on small peptidic GPR54 agonists. Bioorg Med Chem. 2006 Nov 15; 14(22):7595-603.
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Yu BZ, Pan YH, Janssen MJ, Bahnson BJ, Jain MK. Kinetic and structural properties of disulfide engineered phospholipase A2: insight into the role of disulfide bonding patterns. Biochemistry. 2005 Mar 8; 44(9):3369-79.
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Regueiro-Ren A, Naidu BN, Zheng X, Hudyma TW, Connolly TP, Matiskella JD, Zhang Y, Kim OK, Sorenson ME, Pucci M, Clark J, Bronson JJ, Ueda Y. Novel semi-synthetic nocathiacin antibiotics: synthesis and antibacterial activity of bis- and mono-O-alkylated derivatives. Bioorg Med Chem Lett. 2004 Jan 5; 14(1):171-5.
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Chiou SJ, Riordan CG, Rheingold AL. Synthetic modeling of zinc thiolates: quantitative assessment of hydrogen bonding in modulating sulfur alkylation rates. Proc Natl Acad Sci U S A. 2003 Apr 1; 100(7):3695-700.