Alzheimer Disease

"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Descriptor ID	D000544
MeSH Number(s)	C10.228.140.380.100 C10.574.945.249 F03.615.400.100
Concept/Terms	Alzheimer Disease Alzheimer Disease Alzheimer's Disease Dementia, Senile Senile Dementia Dementia, Alzheimer Type Alzheimer Type Dementia Alzheimer-Type Dementia (ATD) Alzheimer Type Dementia (ATD) Dementia, Alzheimer-Type (ATD) Alzheimer Type Senile Dementia Primary Senile Degenerative Dementia Dementia, Primary Senile Degenerative Alzheimer Sclerosis Sclerosis, Alzheimer Alzheimer Syndrome Alzheimer Dementia Alzheimer Dementias Dementia, Alzheimer Dementias, Alzheimer Senile Dementia, Alzheimer Type Acute Confusional Senile Dementia Acute Confusional Senile Dementia Senile Dementia, Acute Confusional Dementia, Presenile Dementia, Presenile Presenile Dementia Alzheimer Disease, Late Onset Alzheimer Disease, Late Onset Late Onset Alzheimer Disease Alzheimer's Disease, Focal Onset Alzheimer's Disease, Focal Onset Focal Onset Alzheimer's Disease Familial Alzheimer Disease (FAD) Familial Alzheimer Disease (FAD) Alzheimer Disease, Familial (FAD) Alzheimer Diseases, Familial (FAD) Familial Alzheimer Diseases (FAD) Alzheimer Disease, Early Onset Alzheimer Disease, Early Onset Early Onset Alzheimer Disease Presenile Alzheimer Dementia

Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".

Diseases [C]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Brain Diseases [C10.228.140]
Dementia [C10.228.140.380]
Alzheimer Disease [C10.228.140.380.100]
Neurodegenerative Diseases [C10.574]
Tauopathies [C10.574.945]
Alzheimer Disease [C10.574.945.249]
Psychiatry and Psychology [F]
Mental Disorders [F03]
Neurocognitive Disorders [F03.615]
Dementia [F03.615.400]
Alzheimer Disease [F03.615.400.100]

Below are MeSH descriptors whose meaning is related to "Alzheimer Disease".

Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.

Bar chart showing 170 publications over 27 distinct years, with a maximum of 16 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	2	1	3
1994	1	0	1
1995	1	0	1
1996	1	0	1
1998	1	1	2
2000	0	1	1
2002	4	2	6
2003	5	0	5
2004	6	3	9
2005	5	2	7
2006	8	2	10
2007	6	3	9
2008	10	3	13
2009	15	1	16
2010	11	3	14
2011	12	2	14
2012	9	1	10
2013	4	0	4
2014	5	1	6
2015	5	1	6
2016	2	2	4
2017	9	0	9
2018	4	0	4
2019	4	0	4
2020	5	1	6
2021	4	0	4
2022	1	0	1

Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.

Bardenheier BH, Resnik LJ, Jutkowitz E, Gravenstein S. Patterns of Limitation in Physical Function in Late Midlife Associated with Late-Onset Alzheimer's Disease and Related Dementias: A Cluster Analysis. J Alzheimers Dis. 2022; 89(4):1331-1338.

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Perez Garcia G, De Gasperi R, Tschiffely AE, Gama Sosa MA, Abutarboush R, Kawoos U, Statz JK, Ciarlone S, Reed E, Jeyarajah T, Perez GM, Otero-Pagan A, Pryor D, Hof PR, Cook DG, Gandy S, Elder GA, Ahlers ST. Repetitive Low-Level Blast Exposure Improves Behavioral Deficits and Chronically Lowers A?42 in an Alzheimer Disease Transgenic Mouse Model. J Neurotrauma. 2021 11 15; 38(22):3146-3173.

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Sergott RC, Raji A, Kost J, Sur C, Jackson S, Locco A, Patel A, Furtek C, Mattson B, Egan MF. Retinal Optical Coherence Tomography Metrics Are Unchanged in Verubecestat Alzheimer's Disease Clinical Trial but Correlate with Baseline Regional Brain Atrophy. J Alzheimers Dis. 2021; 79(1):275-287.

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Llad? A, Froelich L, Khandker RK, Roset M, Black CM, Lara N, Chekani F, Ambegaonkar BM. Assessing the Progression of Alzheimer's Disease in Real-World Settings in Three European Countries. J Alzheimers Dis. 2021; 80(2):749-759.

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Cross DJ, Huber BR, Silverman MA, Cline MM, Gill TB, Cross CG, Cook DG, Minoshima S. Intranasal Paclitaxel Alters Alzheimer's Disease Phenotypic Features in 3xTg-AD Mice. J Alzheimers Dis. 2021; 83(1):379-394.

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Rahman M, White EM, Thomas KS, Jutkowitz E. Assessment of Rural-Urban Differences in Health Care Use and Survival Among Medicare Beneficiaries With Alzheimer Disease and Related Dementia. JAMA Netw Open. 2020 10 01; 3(10):e2022111.

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Sanfilippo C, Castrogiovanni P, Imbesi R, Nunnari G, Di Rosa M. Postsynaptic damage and microglial activation in AD patients could be linked CXCR4/CXCL12 expression levels. Brain Res. 2020 12 15; 1749:147127.

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Halperin JJ, Pascual-Leone A, Saper CB. Symptomatic Hydrocephalus with Normal Cerebrospinal Pressure and Alzheimer's Disease. Ann Neurol. 2020 10; 88(4):685-687.

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Maulik M, Vasan L, Bose A, Dutta Chowdhury S, Sengupta N, Das Sarma J. Amyloid-? regulates gap junction protein connexin 43 trafficking in cultured primary astrocytes. J Biol Chem. 2020 10 30; 295(44):15097-15111.

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Khandker RK, Ritchie CW, Black CM, Wood R, Jones E, Hu X, Ambegaonkar BM. Multi-National, Cross-Sectional Survey of Healthcare Resource Utilization in Patients with All Stages of Cognitive Impairment, Analyzed by Disease Severity, Country, and Geographical Region. J Alzheimers Dis. 2020; 75(4):1141-1152.

View in: PubMed

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