Antigen-Presenting Cells

"Antigen-Presenting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.

Descriptor ID	D000938
MeSH Number(s)	A11.066 A15.382.066
Concept/Terms	Antigen-Presenting Cells Antigen-Presenting Cells Antigen Presenting Cells Antigen-Presenting Cell Cell, Antigen-Presenting Cells, Antigen-Presenting Accessory Cells, Immunologic Immunologic Accessory Cells Cells, Immunologic Accessory Immunologic Accessory Cell Accessory Cell, Immunologic Cell, Immunologic Accessory

Below are MeSH descriptors whose meaning is more general than "Antigen-Presenting Cells".

Anatomy [A]
Cells [A11]
Antigen-Presenting Cells [A11.066]
Hemic and Immune Systems [A15]
Immune System [A15.382]
Antigen-Presenting Cells [A15.382.066]

Below are MeSH descriptors whose meaning is more specific than "Antigen-Presenting Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antigen-Presenting Cells" by people in this website by year, and whether "Antigen-Presenting Cells" was a major or minor topic of these publications.

Bar chart showing 35 publications over 14 distinct years, with a maximum of 6 publications in 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2002	0	3	3
2003	4	2	6
2004	1	2	3
2005	3	1	4
2006	1	0	1
2007	2	2	4
2008	1	2	3
2009	1	1	2
2010	0	2	2
2012	0	1	1
2014	1	1	2
2017	0	1	1
2021	1	1	2

Below are the most recent publications written about "Antigen-Presenting Cells" by people in Profiles.

Knudson CJ, Férez M, Alves-Peixoto P, Erkes DA, Melo-Silva CR, Tang L, Snyder CM, Sigal LJ. Mechanisms of Antiviral Cytotoxic CD4 T Cell Differentiation. J Virol. 2021 09 09; 95(19):e0056621.

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Toulmin SA, Bhadiadra C, Paris AJ, Lin JH, Katzen J, Basil MC, Morrisey EE, Worthen GS, Eisenlohr LC. Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation. Nat Commun. 2021 06 28; 12(1):3993.

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Rezk AF, Kemp DM, El-Domyati M, El-Din WH, Lee JB, Uitto J, Igoucheva O, Alexeev V. Misbalanced CXCL12 and CCL5 Chemotactic Signals in Vitiligo Onset and Progression. J Invest Dermatol. 2017 May; 137(5):1126-1134.

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Ngo MC, Ando J, Leen AM, Ennamuri S, Lapteva N, Vera JF, Min-Venditti A, Mims MP, Heslop HE, Bollard CM, Gottschalk S, Rooney CM. Complementation of antigen-presenting cells to generate T lymphocytes with broad target specificity. J Immunother. 2014 May; 37(4):193-203.

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Mishra A, Sullivan L, Caligiuri MA. Molecular pathways: interleukin-15 signaling in health and in cancer. Clin Cancer Res. 2014 Apr 15; 20(8):2044-50.

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Wanjalla CN, Goldstein EF, Wirblich C, Schnell MJ. A role for granulocyte-macrophage colony-stimulating factor in the regulation of CD8(+) T cell responses to rabies virus. Virology. 2012 May 10; 426(2):120-33.

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Li H, Matte-Martone C, Tan HS, Venkatesan S, McNiff J, Demetris AJ, Jain D, Lakkis F, Rothstein D, Shlomchik WD. Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells. J Immunol. 2011 Jan 01; 186(1):230-41.

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Snyder CM, Allan JE, Bonnett EL, Doom CM, Hill AB. Cross-presentation of a spread-defective MCMV is sufficient to prime the majority of virus-specific CD8+ T cells. PLoS One. 2010; 5(3):e9681.

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Watford WT, Wang CC, Tsatsanis C, Mielke LA, Eliopoulos AG, Daskalakis C, Charles N, Odom S, Rivera J, O'Shea J, Tsichlis PN. Ablation of tumor progression locus 2 promotes a type 2 Th cell response in Ovalbumin-immunized mice. J Immunol. 2010 Jan 1; 184(1):105-13.

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Prendergast GC, Metz R, Muller AJ. IDO recruits Tregs in melanoma. Cell Cycle. 2009 Jun 15; 8(12):1818-9.

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