Antigen-Presenting Cells

"Antigen-Presenting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.

Descriptor ID	D000938
MeSH Number(s)	A11.066 A15.382.066
Concept/Terms	Antigen-Presenting Cells Antigen-Presenting Cells Antigen Presenting Cells Antigen-Presenting Cell Cell, Antigen-Presenting Cells, Antigen-Presenting Accessory Cells, Immunologic Immunologic Accessory Cells Cells, Immunologic Accessory Immunologic Accessory Cell Accessory Cell, Immunologic Cell, Immunologic Accessory

Below are MeSH descriptors whose meaning is more general than "Antigen-Presenting Cells".

Anatomy [A]
Cells [A11]
Antigen-Presenting Cells [A11.066]
Hemic and Immune Systems [A15]
Immune System [A15.382]
Antigen-Presenting Cells [A15.382.066]

Below are MeSH descriptors whose meaning is more specific than "Antigen-Presenting Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antigen-Presenting Cells" by people in this website by year, and whether "Antigen-Presenting Cells" was a major or minor topic of these publications.

Bar chart showing 56 publications over 23 distinct years, with a maximum of 6 publications in 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	1	2
1998	0	2	2
1999	1	3	4
2000	1	1	2
2001	1	0	1
2002	0	3	3
2003	4	2	6
2004	1	2	3
2005	3	1	4
2006	1	0	1
2007	2	2	4
2008	1	2	3
2009	1	1	2
2010	0	3	3
2011	0	1	1
2012	0	1	1
2013	1	1	2
2014	1	3	4
2015	0	2	2
2016	0	1	1
2017	0	1	1
2021	1	2	3
2025	1	0	1

Below are the most recent publications written about "Antigen-Presenting Cells" by people in Profiles.

Johnson BA, Parimi V, Kamanda S, Corney DC, Choi W, Hoffman-Censits J, Kates M, McConkey DJ, Hahn NM, Matoso A. Sarcomatoid areas of urothelial carcinoma are enriched for CD163-positive antigen-presenting cells. J Pathol Clin Res. 2025 Mar; 11(2):e70021.

View in: PubMed
Knudson CJ, F?rez M, Alves-Peixoto P, Erkes DA, Melo-Silva CR, Tang L, Snyder CM, Sigal LJ. Mechanisms of Antiviral Cytotoxic CD4 T Cell Differentiation. J Virol. 2021 09 09; 95(19):e0056621.

View in: PubMed
Toulmin SA, Bhadiadra C, Paris AJ, Lin JH, Katzen J, Basil MC, Morrisey EE, Worthen GS, Eisenlohr LC. Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation. Nat Commun. 2021 06 28; 12(1):3993.

View in: PubMed
Rasouli J, Casella G, Ishikawa LLW, Thome R, Boehm A, Ertel A, Melo-Silva CR, Mari ER, Porazzi P, Zhang W, Xiao D, Sigal LJ, Fortina P, Zhang GX, Rostami A, Ciric B. IFN-? Acts on Monocytes to Ameliorate CNS Autoimmunity by Inhibiting Proinflammatory Cross-Talk Between Monocytes and Th Cells. Front Immunol. 2021; 12:679498.

View in: PubMed
Rezk AF, Kemp DM, El-Domyati M, El-Din WH, Lee JB, Uitto J, Igoucheva O, Alexeev V. Misbalanced CXCL12 and CCL5 Chemotactic Signals in Vitiligo Onset and?Progression. J Invest Dermatol. 2017 05; 137(5):1126-1134.

View in: PubMed
Leitch CS, Natafji E, Yu C, Abdul-Ghaffar S, Madarasingha N, Venables ZC, Chu R, Fitch PM, Muinonen-Martin AJ, Campbell LE, McLean WH, Schwarze J, Howie SE, Weller RB. Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells. J Allergy Clin Immunol. 2016 08; 138(2):482-490.e7.

View in: PubMed
Small EJ, Lance RS, Gardner TA, Karsh LI, Fong L, McCoy C, DeVries T, Sheikh NA, GuhaThakurta D, Chang N, Redfern CH, Shore ND. A Randomized Phase II Trial of Sipuleucel-T with Concurrent versus Sequential Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer. Clin Cancer Res. 2015 Sep 01; 21(17):3862-9.

View in: PubMed
Sawyer DM, Amenta PS, Medel R, Dumont AS. Inflammatory mediators in vascular disease: identifying promising targets for intracranial aneurysm research. Mediators Inflamm. 2015; 2015:896283.

View in: PubMed
Ngo MC, Ando J, Leen AM, Ennamuri S, Lapteva N, Vera JF, Min-Venditti A, Mims MP, Heslop HE, Bollard CM, Gottschalk S, Rooney CM. Complementation of antigen-presenting cells to generate T lymphocytes with broad target specificity. J Immunother. 2014 May; 37(4):193-203.

View in: PubMed
Mishra A, Sullivan L, Caligiuri MA. Molecular pathways: interleukin-15 signaling in health and in cancer. Clin Cancer Res. 2014 Apr 15; 20(8):2044-50.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement