Bradykinin

"Bradykinin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A nonapeptide messenger that is enzymatically produced from KALLIDIN in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from MAST CELLS during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.

Descriptor ID	D001920
MeSH Number(s)	D12.644.276.812.169 D12.644.400.090 D12.644.456.193 D12.776.467.812.169 D12.776.631.650.090 D23.469.050.375.110 D23.529.812.169
Concept/Terms	Bradykinin Bradykinin Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg Arg Pro Pro Gly Phe Ser Pro Phe Arg Bradykinin Diacetate Bradykinin Diacetate Bradykinin Hydrochloride Bradykinin Hydrochloride Bradykinin Triacetate Bradykinin Triacetate Bradykinin, (1-D-Arg)-Isomer Bradykinin, (1-D-Arg)-Isomer Bradykinin, (2-D-Pro)-Isomer Bradykinin, (2-D-Pro)-Isomer Bradykinin, (2-D-Pro-3-D-Pro-7-D-Pro)-Isomer Bradykinin, (2-D-Pro-3-D-Pro-7-D-Pro)-Isomer Bradykinin, (2-D-Pro-7-D-Pro)-Isomer Bradykinin, (2-D-Pro-7-D-Pro)-Isomer Bradykinin, (3-D-Pro)-Isomer Bradykinin, (3-D-Pro)-Isomer Bradykinin, (3-D-Pro-7-D-Pro)-Isomer Bradykinin, (3-D-Pro-7-D-Pro)-Isomer Bradykinin, (5-D-Phe)-Isomer Bradykinin, (5-D-Phe)-Isomer Bradykinin, (5-D-Phe-8-D-Phe)-Isomer Bradykinin, (5-D-Phe-8-D-Phe)-Isomer Bradykinin, (6-D-Ser)-Isomer Bradykinin, (6-D-Ser)-Isomer Bradykinin, (7-D-Pro)-Isomer Bradykinin, (7-D-Pro)-Isomer Bradykinin, (8-D-Phe)-Isomer Bradykinin, (8-D-Phe)-Isomer Bradykinin, (9-D-Arg)-Isomer Bradykinin, (9-D-Arg)-Isomer Bradykinin Acetate, (9-D-Arg)-Isomer Bradykinin Acetate, (9-D-Arg)-Isomer

Below are MeSH descriptors whose meaning is more general than "Bradykinin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Kinins [D12.644.276.812]
Bradykinin [D12.644.276.812.169]
Neuropeptides [D12.644.400]
Bradykinin [D12.644.400.090]
Oligopeptides [D12.644.456]
Bradykinin [D12.644.456.193]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Kinins [D12.776.467.812]
Bradykinin [D12.776.467.812.169]
Nerve Tissue Proteins [D12.776.631]
Neuropeptides [D12.776.631.650]
Bradykinin [D12.776.631.650.090]
Biological Factors [D23]
Inflammation Mediators [D23.469]
Autacoids [D23.469.050]
Kinins [D23.469.050.375]
Bradykinin [D23.469.050.375.110]
Intercellular Signaling Peptides and Proteins [D23.529]
Kinins [D23.529.812]
Bradykinin [D23.529.812.169]

Below are MeSH descriptors whose meaning is related to "Bradykinin".

Below are MeSH descriptors whose meaning is more specific than "Bradykinin".

Bradykinin
Kallidin

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bradykinin" by people in this website by year, and whether "Bradykinin" was a major or minor topic of these publications.

Bar chart showing 12 publications over 8 distinct years, with a maximum of 3 publications in 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	1	2	3
2004	0	1	1
2005	1	1	2
2008	0	2	2
2010	0	1	1
2011	0	1	1
2013	0	1	1
2019	0	1	1

Below are the most recent publications written about "Bradykinin" by people in Profiles.

Perza M, Koczirka S, Nomura JT. C1 Esterase Inhibitor for Ace-Inhibitor Angioedema: A Case Series and Literature Review. J Emerg Med. 2020 Mar; 58(3):e121-e127.

View in: PubMed
Patel NS, Fung SM, Zanichelli A, Cicardi M, Cohn JR. Ecallantide for treatment of acute attacks of acquired C1 esterase inhibitor deficiency. Allergy Asthma Proc. 2013 Jan-Feb; 34(1):72-7.

View in: PubMed
Fuxe J, Tabruyn S, Colton K, Zaid H, Adams A, Baluk P, Lashnits E, Morisada T, Le T, O'Brien S, Epstein DM, Koh GY, McDonald DM. Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation. Am J Pathol. 2011 Jun; 178(6):2897-909.

View in: PubMed
Nagy N, Grattan CE, McGrath JA. New insights into hereditary angio-oedema: Molecular diagnosis and therapy. Australas J Dermatol. 2010 Aug; 51(3):157-62.

View in: PubMed
Simmons BB, Folsom MA, Bryden LA, Studdiford JS. Angioedema after local trauma in a patient on angiotensin-converting enzyme inhibitor therapy. J Am Board Fam Med. 2008 Nov-Dec; 21(6):577-9.

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Jain D, Keslacy S, Tliba O, Cao Y, Kierstein S, Amin K, Panettieri RA, Haczku A, Amrani Y. Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness. Immunobiology. 2008; 213(6):499-509.

View in: PubMed
Huang CD, Ammit AJ, Tliba O, Kuo HP, Penn RB, Panettieri RA, Amrani Y. G-protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-alpha-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells. J Biomed Sci. 2005 Oct; 12(5):763-76.

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Kim JH, Jain D, Tliba O, Yang B, Jester WF, Panettieri RA, Amrani Y, Puré E. TGF-beta potentiates airway smooth muscle responsiveness to bradykinin. Am J Physiol Lung Cell Mol Physiol. 2005 Oct; 289(4):L511-20.

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Babu PB, Chidekel A, Shaffer TH. Protein composition of apical surface fluid from the human airway cell line Calu-3: effect of ion transport mediators. Clin Chim Acta. 2004 Sep; 347(1-2):81-8.

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Tliba O, Deshpande D, Chen H, Van Besien C, Kannan M, Panettieri RA, Amrani Y. IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle. Br J Pharmacol. 2003 Dec; 140(7):1159-62.

View in: PubMed

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