"Cathepsin D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An intracellular proteinase found in a variety of tissue. It has specificity similar to but narrower than that of pepsin A. The enzyme is involved in catabolism of cartilage and connective tissue. EC 3.4.23.5. (Formerly EC 3.4.4.23).
| Descriptor ID |
D002402
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| MeSH Number(s) |
D08.811.277.656.074.500.180 D08.811.277.656.224.187 D08.811.277.656.300.048.180
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cathepsin D".
Below are MeSH descriptors whose meaning is more specific than "Cathepsin D".
This graph shows the total number of publications written about "Cathepsin D" by people in this website by year, and whether "Cathepsin D" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cathepsin D" by people in Profiles.
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Fischer N, Mak TN, Shinohara DB, Sfanos KS, Meyer TF, Br?ggemann H. Deciphering the intracellular fate of Propionibacterium acnes in macrophages. Biomed Res Int. 2013; 2013:603046.
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Colella R, Lu G, Glazewski L, Korant B, Matlapudi A, England MR, Craft C, Frantz CN, Mason RW. Induction of cell death in neuroblastoma by inhibition of cathepsins B and L. Cancer Lett. 2010 Aug 28; 294(2):195-203.
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Wei P, Smeyne RJ, Bao D, Parris J, Morgan JI. Mapping of Cbln1-like immunoreactivity in adult and developing mouse brain and its localization to the endolysosomal compartment of neurons. Eur J Neurosci. 2007 Nov; 26(10):2962-78.
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Harris L, Fritsche H, Mennel R, Norton L, Ravdin P, Taube S, Somerfield MR, Hayes DF, Bast RC. American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer. J Clin Oncol. 2007 Nov 20; 25(33):5287-312.
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Esteva FJ, Sahin AA, Cristofanilli M, Arun B, Hortobagyi GN. Molecular prognostic factors for breast cancer metastasis and survival. Semin Radiat Oncol. 2002 Oct; 12(4):319-28.
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Cataldo AM, Barnett JL, Berman SA, Li J, Quarless S, Bursztajn S, Lippa C, Nixon RA. Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system. Neuron. 1995 Mar; 14(3):671-80.
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Hock CE, Beck LD, Holahan MA, Reibel DK. Dietary oils: effects on lethal superior mesenteric artery occlusion shock in the rat. Prog Clin Biol Res. 1988; 264:425-31.
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Hock CE, Curtis MT, Jaffe JS, Lefer AM. Beneficial actions of nalorphine during hemorrhagic shock in cats. Proc Soc Exp Biol Med. 1983 May; 173(1):76-81.
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Curtis MT, Lefer AM. Effectiveness of ethylketocyclazocine in hemorrhagic shock. Adv Shock Res. 1983; 10:101-9.
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Curtis MT, Lefer AM. Actions of opiate antagonists with selective receptor interactions in hemorrhagic shock. Circ Shock. 1983; 10(2):131-45.