Choline

"Choline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

Descriptor ID	D002794
MeSH Number(s)	D02.033.100.291.211 D02.092.063.291.211 D02.092.877.883.333 D02.675.276.232
Concept/Terms	Choline Choline 2-Hydroxy-N,N,N-trimethylethanaminium Choline Citrate Choline Citrate Citrate, Choline Choline O-Sulfate Choline O-Sulfate Choline O Sulfate O-Sulfate, Choline Choline Hydroxide Choline Hydroxide Hydroxide, Choline Bursine Bursine Vidine Fagine Choline Bitartrate Choline Bitartrate Bitartrate, Choline Choline Chloride Choline Chloride Chloride, Choline

Below are MeSH descriptors whose meaning is more general than "Choline".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Alcohols [D02.033]
Amino Alcohols [D02.033.100]
Ethanolamines [D02.033.100.291]
Choline [D02.033.100.291.211]
Amines [D02.092]
Amino Alcohols [D02.092.063]
Ethanolamines [D02.092.063.291]
Choline [D02.092.063.291.211]
Quaternary Ammonium Compounds [D02.092.877]
Trimethyl Ammonium Compounds [D02.092.877.883]
Choline [D02.092.877.883.333]
Onium Compounds [D02.675]
Quaternary Ammonium Compounds [D02.675.276]
Choline [D02.675.276.232]

Below are MeSH descriptors whose meaning is related to "Choline".

Below are MeSH descriptors whose meaning is more specific than "Choline".

Choline
Platelet Activating Factor

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Choline" by people in this website by year, and whether "Choline" was a major or minor topic of these publications.

Bar chart showing 14 publications over 11 distinct years, with a maximum of 2 publications in 2013 and 2016 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2001	0	1	1
2002	0	1	1
2006	0	1	1
2008	0	1	1
2009	0	1	1
2010	0	1	1
2013	1	1	2
2016	1	1	2
2019	2	0	2
2023	0	1	1

Below are the most recent publications written about "Choline" by people in Profiles.

Chaganti J, Zeng G, Tun N, Lockart I, Abdelshaheed C, Cysique L, Montagnese S, Brew BJ, Danta M. Novel magnetic resonance KTRANS measurement of blood-brain barrier permeability correlated with covert HE. Hepatol Commun. 2023 04 01; 7(4).

View in: PubMed
Faiq MA, Wollstein G, Schuman JS, Chan KC. Cholinergic nervous system and glaucoma: From basic science to clinical applications. Prog Retin Eye Res. 2019 09; 72:100767.

View in: PubMed
Chawla S, Lee SC, Mohan S, Wang S, Nasrallah M, Vossough A, Krejza J, Melhem ER, Nabavizadeh SA. Lack of choline elevation on proton magnetic resonance spectroscopy in grade I-III gliomas. Neuroradiol J. 2019 08; 32(4):250-258.

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Murphy MC, Conner IP, Teng CY, Lawrence JD, Safiullah Z, Wang B, Bilonick RA, Kim SG, Wollstein G, Schuman JS, Chan KC. Retinal Structures and Visual Cortex Activity are Impaired Prior to Clinical Vision Loss in Glaucoma. Sci Rep. 2016 08 11; 6:31464.

View in: PubMed
Trousil S, Kaliszczak M, Schug Z, Nguyen QD, Tomasi G, Favicchio R, Brickute D, Fortt R, Twyman FJ, Carroll L, Kalusa A, Navaratnam N, Adejumo T, Carling D, Gottlieb E, Aboagye EO. The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth. Oncotarget. 2016 Jun 14; 7(24):37103-37120.

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Song P, Rekow SS, Singleton CA, Sekhon HS, Dissen GA, Zhou M, Campling B, Lindstrom J, Spindel ER. Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis. J Neurochem. 2013 Aug; 126(4):451-61.

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Verma G, Woo JH, Chawla S, Wang S, Sheriff S, Elman LB, McCluskey LF, Grossman M, Melhem ER, Maudsley AA, Poptani H. Whole-brain analysis of amyotrophic lateral sclerosis by using echo-planar spectroscopic imaging. Radiology. 2013 Jun; 267(3):851-7.

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Chawla S, Zhang Y, Wang S, Chaudhary S, Chou C, O'Rourke DM, Vossough A, Melhem ER, Poptani H. Proton magnetic resonance spectroscopy in differentiating glioblastomas from primary cerebral lymphomas and brain metastases. J Comput Assist Tomogr. 2010 Nov-Dec; 34(6):836-41.

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Chawla S, Wang S, Moore P, Woo JH, Elman L, McCluskey LF, Melhem ER, Grossman M, Poptani H. Quantitative proton magnetic resonance spectroscopy detects abnormalities in dorsolateral prefrontal cortex and motor cortex of patients with frontotemporal lobar degeneration. J Neurol. 2010 Jan; 257(1):114-21.

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Batista CE, Chugani HT, Hu J, Haacke EM, Behen ME, Helder EJ, Juh?sz C. Magnetic resonance spectroscopic imaging detects abnormalities in normal-appearing frontal lobe of patients with Sturge-Weber syndrome. J Neuroimaging. 2008 Jul; 18(3):306-13.

View in: PubMed

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