Citric Acid Cycle

"Citric Acid Cycle" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A series of oxidative reactions in the breakdown of acetyl units derived from GLUCOSE; FATTY ACIDS; or AMINO ACIDS by means of tricarboxylic acid intermediates. The end products are CARBON DIOXIDE, water, and energy in the form of phosphate bonds.

Descriptor ID	D002952
MeSH Number(s)	G02.111.165 G03.295.342 G03.493.170
Concept/Terms	Citric Acid Cycle Citric Acid Cycle Citric Acid Cycles Cycle, Citric Acid Cycles, Citric Acid Tricarboxylic Acid Cycle Cycle, Tricarboxylic Acid Cycles, Tricarboxylic Acid Tricarboxylic Acid Cycles Krebs Cycle Cycle, Krebs

Below are MeSH descriptors whose meaning is more general than "Citric Acid Cycle".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Citric Acid Cycle [G02.111.165]
Metabolism [G03]
Energy Metabolism [G03.295]
Citric Acid Cycle [G03.295.342]
Metabolic Networks and Pathways [G03.493]
Citric Acid Cycle [G03.493.170]

Below are MeSH descriptors whose meaning is related to "Citric Acid Cycle".

Below are MeSH descriptors whose meaning is more specific than "Citric Acid Cycle".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Citric Acid Cycle" by people in this website by year, and whether "Citric Acid Cycle" was a major or minor topic of these publications.

Bar chart showing 5 publications over 3 distinct years, with a maximum of 2 publications in 2004 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	0	2	2
2010	1	0	1
2011	0	2	2

Below are the most recent publications written about "Citric Acid Cycle" by people in Profiles.

Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, Barretina J, Kalaany NY, Hsu PP, Ottina K, Chan AM, Yuan B, Garraway LA, Root DE, Mino-Kenudson M, Brachtel EF, Driggers EM, Sabatini DM. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature. 2011 Aug 18; 476(7360):346-50.

View in: PubMed
Martinez-Outschoorn UE, Prisco M, Ertel A, Tsirigos A, Lin Z, Pavlides S, Wang C, Flomenberg N, Knudsen ES, Howell A, Pestell RG, Sotgia F, Lisanti MP. Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics. Cell Cycle. 2011 Apr 15; 10(8):1271-86.

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Crown SB, Indurthi DC, Ahn WS, Choi J, Papoutsakis ET, Antoniewicz MR. Resolving the TCA cycle and pentose-phosphate pathway of Clostridium acetobutylicum ATCC 824: Isotopomer analysis, in vitro activities and expression analysis. Biotechnol J. 2011 Mar; 6(3):300-5.

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Malthankar GV, White BK, Bhushan A, Daniels CK, Rodnick KJ, Lai JC. Differential lowering by manganese treatment of activities of glycolytic and tricarboxylic acid (TCA) cycle enzymes investigated in neuroblastoma and astrocytoma cells is associated with manganese-induced cell death. Neurochem Res. 2004 Apr; 29(4):709-17.

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Wong MS, Raab RM, Rigoutsos I, Stephanopoulos GN, Kelleher JK. Metabolic and transcriptional patterns accompanying glutamine depletion and repletion in mouse hepatoma cells: a model for physiological regulatory networks. Physiol Genomics. 2004 Jan 15; 16(2):247-55.

View in: PubMed

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