Ehlers-Danlos Syndrome

"Ehlers-Danlos Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A heterogeneous group of autosomally inherited COLLAGEN DISEASES caused by defects in the synthesis or structure of FIBRILLAR COLLAGEN. There are numerous subtypes: classical, hypermobility, vascular, and others. Common clinical features include hyperextensible skin and joints, skin fragility and reduced wound healing capability.

Descriptor ID	D004535
MeSH Number(s)	C14.907.454.240 C15.378.463.515.240 C16.131.831.428 C16.320.850.260 C17.300.200.310 C17.800.804.428 C17.800.827.260
Concept/Terms	Ehlers-Danlos Syndrome Ehlers-Danlos Syndrome Ehlers Danlos Syndrome Syndrome, Ehlers-Danlos Cutis Elastica Ehlers Danlos Disease Danlos Disease, Ehlers Disease, Ehlers Danlos Ehlers-Danlos Disease Disease, Ehlers-Danlos Ehlers-Danlos Syndrome, Type IV Ehlers-Danlos Syndrome, Type IV Ehlers Danlos Syndrome, Type IV Ehlers-Danlos Syndrome, Arterial Type Ehlers-Danlos Syndrome, Ecchymotic Type Ehlers-Danlos Syndrome, Sack-Barabas Type Ehlers Danlos Syndrome, Sack-Barabas Type Ehlers Danlos Syndrome, Sack Barabas Type Ehlers-Danlos Syndrome, Type IV, Autosomal Dominant Ehlers Danlos Syndrome Type 4, Autosomal Dominant Ehlers Danlos Syndrome, Arterial Type Ehlers Danlos Syndrome, Ecchymotic Type Ehlers-Danlos Syndrome, Vascular Type Ehlers Danlos Syndrome, Vascular Type EDS IV

Below are MeSH descriptors whose meaning is more general than "Ehlers-Danlos Syndrome".

Diseases [C]
Cardiovascular Diseases [C14]
Vascular Diseases [C14.907]
Hemostatic Disorders [C14.907.454]
Ehlers-Danlos Syndrome [C14.907.454.240]
Hemic and Lymphatic Diseases [C15]
Hematologic Diseases [C15.378]
Hemorrhagic Disorders [C15.378.463]
Hemostatic Disorders [C15.378.463.515]
Ehlers-Danlos Syndrome [C15.378.463.515.240]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Congenital Abnormalities [C16.131]
Skin Abnormalities [C16.131.831]
Ehlers-Danlos Syndrome [C16.131.831.428]
Genetic Diseases, Inborn [C16.320]
Skin Diseases, Genetic [C16.320.850]
Ehlers-Danlos Syndrome [C16.320.850.260]
Skin and Connective Tissue Diseases [C17]
Connective Tissue Diseases [C17.300]
Collagen Diseases [C17.300.200]
Ehlers-Danlos Syndrome [C17.300.200.310]
Skin Diseases [C17.800]
Skin Abnormalities [C17.800.804]
Ehlers-Danlos Syndrome [C17.800.804.428]
Skin Diseases, Genetic [C17.800.827]
Ehlers-Danlos Syndrome [C17.800.827.260]

Below are MeSH descriptors whose meaning is related to "Ehlers-Danlos Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Ehlers-Danlos Syndrome".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ehlers-Danlos Syndrome" by people in this website by year, and whether "Ehlers-Danlos Syndrome" was a major or minor topic of these publications.

Bar chart showing 9 publications over 9 distinct years, with a maximum of 1 publications in 2002 and 2007 and 2009 and 2011 and 2012 and 2013 and 2014 and 2016 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2007	1	0	1
2009	1	0	1
2011	0	1	1
2012	1	0	1
2013	0	1	1
2014	0	1	1
2016	0	1	1
2018	0	1	1

Below are the most recent publications written about "Ehlers-Danlos Syndrome" by people in Profiles.

Chen A, Fertala A, Abboud J, Wang M, Rivlin M, Beredjiklian PK. The Molecular Basis of Genetic Collagen Disorders and Its Clinical Relevance. J Bone Joint Surg Am. 2018 Jun 06; 100(11):976-986.

View in: PubMed
Weinsaft JW, Devereux RB, Preiss LR, Feher A, Roman MJ, Basson CT, Geevarghese A, Ravekes W, Dietz HC, Holmes K, Habashi J, Pyeritz RE, Bavaria J, Milewski K, LeMaire SA, Morris S, Milewicz DM, Prakash S, Maslen C, Song HK, Silberbach GM, Shohet RV, McDonnell N, Hendershot T, Eagle KA, Asch FM. Aortic Dissection in Patients With Genetically Mediated Aneurysms: Incidence and Predictors in the GenTAC Registry. J Am Coll Cardiol. 2016 06 14; 67(23):2744-2754.

View in: PubMed
Nikolovska K, Renke JK, Jungmann O, Grobe K, Iozzo RV, Zamfir AD, Seidler DG. A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function. Matrix Biol. 2014 Apr; 35:91-102.

View in: PubMed
Wu Z, Horgan CE, Carr O, Owens RT, Iozzo RV, Lechner BE. Biglycan and decorin differentially regulate signaling in the fetal membranes. Matrix Biol. 2014 Apr; 35:266-75.

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Sherif HM, Blackwell RA. Successful coronary artery bypass in Ehlers-Danlos type IV syndrome case report and review of the literature. Tex Heart Inst J. 2012; 39(5):699-702.

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Calmus ML, Macksoud EE, Tucker R, Iozzo RV, Lechner BE. A mouse model of spontaneous preterm birth based on the genetic ablation of biglycan and decorin. Reproduction. 2011 Jul; 142(1):183-94.

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Badawi RA, Brent LH, Feinstein DE. Mimics of vasculitis: vascular Ehlers-Danlos syndrome masquerading as polyarteritis nodosa. J Rheumatol. 2009 Aug; 36(8):1845-7.

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Cabral WA, Makareeva E, Letocha AD, Scribanu N, Fertala A, Steplewski A, Keene DR, Persikov AV, Leikin S, Marini JC. Y-position cysteine substitution in type I collagen (alpha1(I) R888C/p.R1066C) is associated with osteogenesis imperfecta/Ehlers-Danlos syndrome phenotype. Hum Mutat. 2007 Apr; 28(4):396-405.

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Corsi A, Xu T, Chen XD, Boyde A, Liang J, Mankani M, Sommer B, Iozzo RV, Eichstetter I, Robey PG, Bianco P, Young MF. Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues. J Bone Miner Res. 2002 Jul; 17(7):1180-9.

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Sarra-Carbonell S, Jimenez SA. Ehlers-Danlos syndrome associated with acute pancreatitis. J Rheumatol. 1989 Oct; 16(10):1390-4.

View in: PubMed

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