"Factor V" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.
| Descriptor ID |
D005165
|
| MeSH Number(s) |
D12.776.124.125.300 D23.119.300
|
| Concept/Terms |
Factor V- Factor V
- Factor Five
- Five, Factor
- AC Globulin
- Blood Coagulation Factor V
- Factor Pi
- Proaccelerin
- Factor 5
- Coagulation Factor V
- Factor V, Coagulation
|
Below are MeSH descriptors whose meaning is more general than "Factor V".
Below are MeSH descriptors whose meaning is more specific than "Factor V".
This graph shows the total number of publications written about "Factor V" by people in this website by year, and whether "Factor V" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 2 | 1 | 3 |
| 2003 | 0 | 1 | 1 |
| 2005 | 2 | 2 | 4 |
| 2008 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Factor V" by people in Profiles.
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Patounakis G, Bergh E, Forman EJ, Tao X, Lonczak A, Franasiak JM, Treff N, Scott RT. Multiple thrombophilic single nucleotide polymorphisms lack a significant effect on outcomes in fresh IVF cycles: an analysis of 1717 patients. J Assist Reprod Genet. 2016 Jan; 33(1):67-73.
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Slamon N, Krueger LJ, Edelson M, Glutting JJ, Rittenhouse D. A retrospective study of the factors associated with hypercoagulability in the pediatric patients at a tertiary care children's hospital. Pediatr Crit Care Med. 2008 Sep; 9(5):511-6.
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Preston FE, Jennings I, Kitchen DP, Woods TA, Kitchen S. Variability in factor V:C assays in UK National External Quality Assessment Scheme surveys: there is a need for an international standard. Blood Coagul Fibrinolysis. 2005 Oct; 16(7):529-31.
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Dunn SP, Tsai A, Griffin G, Toth S, Casas-Melley AT, Falkenstein KP, Marando CA, Krueger LJ. Liver transplantation as definitive treatment for a factor V Leiden mutation. J Pediatr. 2005 Mar; 146(3):418-22.
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Jennings I, Kitchen S, Woods TA, Preston FE. Multilaboratory testing in thrombophilia through the United Kingdom National External Quality Assessment Scheme (Blood Coagulation) Quality Assurance Program. Semin Thromb Hemost. 2005 Feb; 31(1):66-72.
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Keller MA. Molecular diagnostic testing for inherited thrombophilia using Invader. Methods Mol Med. 2005; 114:107-19.
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Moster ML. Coagulopathies and arterial stroke. J Neuroophthalmol. 2003 Mar; 23(1):63-71.
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Tan HP, Markowitz JS, Maley WR, Merritt WT, Klein AS. Successful liver transplantation in a patient with Budd-Chiari syndrome caused by homozygous factor V Leiden. Liver Transpl. 2000 Sep; 6(5):654-6.
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Corseaux D, Meurice T, Six I, Rugeri L, Ezekowitz MD, Rouvier P, Bordet R, Bauters C, Jude B. Basic fibroblast growth factor increases tissue factor expression in circulating monocytes and in vascular wall. Circulation. 2000 Apr 25; 101(16):2000-6.
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Jennings I, Kitchen S, Cooper PC, Rimmer JE, Woods TA, Preston FE. Further evidence that activated protein C resistance affects protein C coagulant activity assays. Thromb Haemost. 2000 Jan; 83(1):171-2.