Hydroxyeicosatetraenoic Acids
"Hydroxyeicosatetraenoic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Eicosatetraenoic acids substituted in any position by one or more hydroxy groups. They are important intermediates in a series of biosynthetic processes leading from arachidonic acid to a number of biologically active compounds such as prostaglandins, thromboxanes, and leukotrienes.
| Descriptor ID |
D006893
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| MeSH Number(s) |
D10.251.355.255.100.300 D10.251.355.310.166.550
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hydroxyeicosatetraenoic Acids".
Below are MeSH descriptors whose meaning is more specific than "Hydroxyeicosatetraenoic Acids".
This graph shows the total number of publications written about "Hydroxyeicosatetraenoic Acids" by people in this website by year, and whether "Hydroxyeicosatetraenoic Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Hydroxyeicosatetraenoic Acids" by people in Profiles.
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Perry SC, Horn T, Tourdot BE, Yamaguchi A, Kalyanaraman C, Conrad WS, Akinkugbe O, Holinstat M, Jacobson MP, Holman TR. Role of Human 15-Lipoxygenase-2 in the Biosynthesis of the Lipoxin Intermediate, 5S,15S-diHpETE, Implicated with the Altered Positional Specificity of Human 15-Lipoxygenase-1. Biochemistry. 2020 10 27; 59(42):4118-4130.
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Afshinnia F, Zeng L, Byun J, Wernisch S, Deo R, Chen J, Hamm L, Miller ER, Rhee EP, Fischer MJ, Sharma K, Feldman HI, Michailidis G, Pennathur S. Elevated lipoxygenase and cytochrome P450 products predict progression of chronic kidney disease. Nephrol Dial Transplant. 2020 02 01; 35(2):303-312.
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Green AR, Freedman C, Tena J, Tourdot BE, Liu B, Holinstat M, Holman TR. 5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1. Biochemistry. 2018 12 04; 57(48):6726-6734.
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Moon SH, Liu X, Cedars AM, Yang K, Kiebish MA, Joseph SM, Kelley J, Jenkins CM, Gross RW. Heart failure-induced activation of phospholipase iPLA2? generates hydroxyeicosatetraenoic acids opening the mitochondrial permeability transition pore. J Biol Chem. 2018 01 05; 293(1):115-129.
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Yu M, Lopez B, Dos Santos EA, Falck JR, Roman RJ. Effects of 20-HETE on Na+ transport and Na+ -K+ -ATPase activity in the thick ascending loop of Henle. Am J Physiol Regul Integr Comp Physiol. 2007 Jun; 292(6):R2400-5.
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Jacobs ER, Zhu D, Gruenloh S, Lopez B, Medhora M. VEGF-induced relaxation of pulmonary arteries is mediated by endothelial cytochrome P-450 hydroxylase. Am J Physiol Lung Cell Mol Physiol. 2006 Sep; 291(3):L369-77.
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Scalia R, Gefen J, Petasis NA, Serhan CN, Lefer AM. Lipoxin A4 stable analogs inhibit leukocyte rolling and adherence in the rat mesenteric microvasculature: role of P-selectin. Proc Natl Acad Sci U S A. 1997 Sep 02; 94(18):9967-72.
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Hotter G, Closa D, Pi F, Rosell?-Catafau J, Bulbena O, Badosa F, Fern?ndez-Cruz L, Gelp? E. Arachidonate metabolism in ischemia-reperfusion associated with pancreas transplantation. J Lipid Mediat Cell Signal. 1994 Mar; 9(2):135-43.