Arachidonic Acid

"Arachidonic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.

Descriptor ID	D016718
MeSH Number(s)	D10.251.355.255.100.100 D10.251.355.310.166.100
Concept/Terms	Arachidonic Acid Arachidonic Acid Vitamin F (all-Z)-5,8,11,14-Eicosatetraenoic acid Arachidonic Acid, Sodium Salt, (all-Z)-Isomer Arachidonic Acid, Sodium Salt, (all-Z)-Isomer Arachidonic Acid, Sodium Salt Arachidonic Acid, Sodium Salt Sodium Arachidonate Arachidonate, Sodium Arachidonic Acid, Zinc Salt, (all-Z)-Isomer Arachidonic Acid, Zinc Salt, (all-Z)-Isomer Arachidonic Acid, Lithium Salt, (all-Z)-Isomer Arachidonic Acid, Lithium Salt, (all-Z)-Isomer Arachidonic Acid, (all-Z)-Isomer, 1-(14)C-Labeled Arachidonic Acid, (all-Z)-Isomer, 1-(14)C-Labeled Arachidonic Acid, Cerium Salt, (all-Z)-Isomer Arachidonic Acid, Cerium Salt, (all-Z)-Isomer Arachidonic Acid, Cesium Salt, (all-Z)-Isomer Arachidonic Acid, Cesium Salt, (all-Z)-Isomer Arachidonic Acid, Potassium Salt, (all-Z)-Isomer Arachidonic Acid, Potassium Salt, (all-Z)-Isomer Arachidonic Acid, Ammonium Salt, (all-Z)-Isomer Arachidonic Acid, Ammonium Salt, (all-Z)-Isomer Arachidonic Acid, (all-Z)-isomer, 3H-Labeled Arachidonic Acid, (all-Z)-isomer, 3H-Labeled

Below are MeSH descriptors whose meaning is more general than "Arachidonic Acid".

Chemicals and Drugs [D]
Lipids [D10]
Fatty Acids [D10.251]
Fatty Acids, Unsaturated [D10.251.355]
Eicosanoids [D10.251.355.255]
Arachidonic Acids [D10.251.355.255.100]
Arachidonic Acid [D10.251.355.255.100.100]
Fatty Acids, Essential [D10.251.355.310]
Arachidonic Acids [D10.251.355.310.166]
Arachidonic Acid [D10.251.355.310.166.100]

Below are MeSH descriptors whose meaning is related to "Arachidonic Acid".

Below are MeSH descriptors whose meaning is more specific than "Arachidonic Acid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Arachidonic Acid" by people in this website by year, and whether "Arachidonic Acid" was a major or minor topic of these publications.

Bar chart showing 23 publications over 17 distinct years, with a maximum of 2 publications in 2006 and 2009 and 2012 and 2015 and 2016 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2001	0	1	1
2003	1	0	1
2005	0	1	1
2006	0	2	2
2007	0	1	1
2009	1	1	2
2010	0	1	1
2011	0	1	1
2012	1	1	2
2013	0	1	1
2015	1	1	2
2016	0	2	2
2019	0	2	2
2020	0	1	1
2021	0	1	1
2023	0	1	1

Below are the most recent publications written about "Arachidonic Acid" by people in Profiles.

Mobbs JI, Black KA, Tran M, Burger WAC, Venugopal H, Holman TR, Holinstat M, Thal DM, Glukhova A. Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors. Blood. 2023 10 05; 142(14):1233-1242.

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Tsai WC, Kalyanaraman C, Yamaguchi A, Holinstat M, Jacobson MP, Holman TR. In Vitro Biosynthetic Pathway Investigations of Neuroprotectin D1 (NPD1) and Protectin DX (PDX) by Human 12-Lipoxygenase, 15-Lipoxygenase-1, and 15-Lipoxygenase-2. Biochemistry. 2021 06 08; 60(22):1741-1754.

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Perry SC, Horn T, Tourdot BE, Yamaguchi A, Kalyanaraman C, Conrad WS, Akinkugbe O, Holinstat M, Jacobson MP, Holman TR. Role of Human 15-Lipoxygenase-2 in the Biosynthesis of the Lipoxin Intermediate, 5S,15S-diHpETE, Implicated with the Altered Positional Specificity of Human 15-Lipoxygenase-1. Biochemistry. 2020 10 27; 59(42):4118-4130.

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Setty BNY, Betal SG, Miller RE, Brown DS, Meier M, Cahill M, Lerner NB, Apollonsky N, Stuart MJ. Relationship of Omega-3 fatty acids DHA and EPA with the inflammatory biomarker hs-CRP in children with sickle cell anemia. Prostaglandins Leukot Essent Fatty Acids. 2019 07; 146:11-18.

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Veglia F, Tyurin VA, Blasi M, De Leo A, Kossenkov AV, Donthireddy L, To TKJ, Schug Z, Basu S, Wang F, Ricciotti E, DiRusso C, Murphy ME, Vonderheide RH, Lieberman PM, Mulligan C, Nam B, Hockstein N, Masters G, Guarino M, Lin C, Nefedova Y, Black P, Kagan VE, Gabrilovich DI. Fatty acid transport protein?2 reprograms neutrophils in cancer. Nature. 2019 05; 569(7754):73-78.

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Edelstein LC. The role of platelet microvesicles in intercellular communication. Platelets. 2017 May; 28(3):222-227.

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Kraft WK, Gilmartin JH, Chappell DL, Gheyas F, Walker BM, Nagalla S, Naik UP, Horrow JC, Wrishko RE, Zhang S, Anderson MS. Effect of Vorapaxar Alone and in Combination with Aspirin on Bleeding Time and Platelet Aggregation in Healthy Adult Subjects. Clin Transl Sci. 2016 08; 9(4):221-7.

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Rattan S, Singh J, Kumar S, Phillips B. Nature of extracellular signal that triggers RhoA/ROCK activation for the basal internal anal sphincter tone in humans. Am J Physiol Gastrointest Liver Physiol. 2015 Jun 01; 308(11):G924-33.

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Qayyum R, Becker LC, Becker DM, Faraday N, Yanek LR, Leal SM, Shaw C, Mathias R, Suktitipat B, Bray PF. Genome-wide association study of platelet aggregation in African Americans. BMC Genet. 2015 May 30; 16:58.

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Jacobs BR, Nadkarni V, Goldstein B, Checchia P, Ayad O, Bean J, DeMichele S. Nutritional immunomodulation in critically ill children with acute lung injury: feasibility and impact on circulating biomarkers. Pediatr Crit Care Med. 2013 Jan; 14(1):e45-56.

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