Below are the most recent publications written about "DNA Ligases" by people in Profiles.
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Rashid I, Tsai MS, Sverzhinsky A, Hlaing AS, Shih B, Thwin AC, Lin JG, Maw SS, Pascal JM, Tomkinson AE. Purification and Characterization of Human DNA Ligase IIIa Complexes After Expression in Insect Cells. Methods Mol Biol. 2022; 2444:243-269.
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Sverzhinsky A, Tomkinson AE, Pascal JM. Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure. 2022 03 03; 30(3):371-385.e5.
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Matsumoto Y, Brooks RC, Sverzhinsky A, Pascal JM, Tomkinson AE. Dynamic DNA-bound PCNA complexes co-ordinate Okazaki fragment synthesis, processing and ligation. J Mol Biol. 2020 12 04; 432(24):166698.
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Grupp K, Roettger L, Kluth M, Hube-Magg C, Simon R, Lebok P, Minner S, Tsourlakis MC, Koop C, Graefen M, Adam M, Haese A, Wittmer C, Sauter G, Wilczak W, Huland H, Schlomm T, Steurer S, Krech T. Expression of DNA ligase IV is linked to poor prognosis and characterizes a subset of prostate cancers harboring TMPRSS2:ERG fusion and PTEN deletion. Oncol Rep. 2015 Sep; 34(3):1211-20.
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Murray JE, Bicknell LS, Yigit G, Duker AL, van Kogelenberg M, Haghayegh S, Wieczorek D, Kayserili H, Albert MH, Wise CA, Brandon J, Kleefstra T, Warris A, van der Flier M, Bamforth JS, Doonanco K, Ad?s L, Ma A, Field M, Johnson D, Shackley F, Firth H, Woods CG, N?rnberg P, Gatti RA, Hurles M, Bober MB, Wollnik B, Jackson AP. Extreme growth failure is a common presentation of ligase IV deficiency. Hum Mutat. 2014 Jan; 35(1):76-85.
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Podos SD, Thanassi JA, Pucci MJ. Mechanistic assessment of DNA ligase as an antibacterial target in Staphylococcus aureus. Antimicrob Agents Chemother. 2012 Aug; 56(8):4095-102.
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Song W, Pascal JM, Ellenberger T, Tomkinson AE. The DNA binding domain of human DNA ligase I interacts with both nicked DNA and the DNA sliding clamps, PCNA and hRad9-hRad1-hHus1. DNA Repair (Amst). 2009 Aug 06; 8(8):912-9.
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Pascal JM. DNA and RNA ligases: structural variations and shared mechanisms. Curr Opin Struct Biol. 2008 Feb; 18(1):96-105.
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Buguliskis JS, Casta LJ, Butz CE, Matsumoto Y, Taraschi TF. Expression and biochemical characterization of Plasmodium falciparum DNA ligase I. Mol Biochem Parasitol. 2007 Oct; 155(2):128-37.
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Roberts SA, Ramsden DA. Loading of the nonhomologous end joining factor, Ku, on protein-occluded DNA ends. J Biol Chem. 2007 Apr 06; 282(14):10605-13.