"Fibromodulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small leucine-rich proteoglycan that contains 4 KERATAN SULFATE chains within the leucine repeat region. It interacts with COLLAGEN TYPE I and COLLAGEN TYPE II fibrils and may function to control the rate of EXTRACELLULAR MATRIX assembly. It also sequesters TRANSFORMING GROWTH FACTOR BETA in the extracellular matrix.
| Descriptor ID |
D000071235
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| MeSH Number(s) |
D09.698.735.700.813 D12.776.395.650.875.625 D12.776.860.300.806.813
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fibromodulin".
Below are MeSH descriptors whose meaning is more specific than "Fibromodulin".
This graph shows the total number of publications written about "Fibromodulin" by people in this website by year, and whether "Fibromodulin" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fibromodulin" by people in Profiles.
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Colon-Caraballo M, Lee N, Nallasamy S, Myers K, Hudson D, Iozzo RV, Mahendroo M. Novel regulatory roles of small leucine-rich proteoglycans in remodeling of the uterine cervix in pregnancy. Matrix Biol. 2022 01; 105:53-71.
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Schaefer L. Small leucine-rich proteoglycans in kidney disease. J Am Soc Nephrol. 2011 Jul; 22(7):1200-7.
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Sch?nherr E, Sunderk?tter C, Schaefer L, Thanos S, Gr?ssel S, Oldberg A, Iozzo RV, Young MF, Kresse H. Decorin deficiency leads to impaired angiogenesis in injured mouse cornea. J Vasc Res. 2004 Nov-Dec; 41(6):499-508.
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Chakravarti S, Paul J, Roberts L, Chervoneva I, Oldberg A, Birk DE. Ocular and scleral alterations in gene-targeted lumican-fibromodulin double-null mice. Invest Ophthalmol Vis Sci. 2003 Jun; 44(6):2422-32.
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Ezura Y, Chakravarti S, Oldberg A, Chervoneva I, Birk DE. Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons. J Cell Biol. 2000 Nov 13; 151(4):779-88.