Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome
"Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The largest subunit of the anaphase-promoting complex. It acts primarily as a scaffold for the proper organization and arrangement of subunits. The C-terminal region of Apc1 contains a series of tandem amino acid repeats that are also seen in the 26S proteasome regulatory particle, and may assist with forming and stabilizing protein-protein interactions.
| Descriptor ID |
D064189
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| MeSH Number(s) |
D08.811.464.938.750.092.500 D12.776.167.024.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome".
Below are MeSH descriptors whose meaning is more specific than "Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome".
This graph shows the total number of publications written about "Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in this website by year, and whether "Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in Profiles.
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Hankey W, McIlhatton MA, Ebede K, Kennedy B, Hancioglu B, Zhang J, Brock GN, Huang K, Groden J. Mutational Mechanisms That Activate Wnt Signaling and Predict Outcomes in Colorectal Cancer Patients. Cancer Res. 2018 02 01; 78(3):617-630.