Interleukin-6

"Interleukin-6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.

Descriptor ID	D015850
MeSH Number(s)	D12.644.276.374.465.224 D12.776.467.374.465.202 D23.529.374.465.224
Concept/Terms	Interleukin-6 Interleukin-6 Interleukin 6 IL6 B-Cell Stimulatory Factor 2 B-Cell Stimulatory Factor-2 Differentiation Factor-2, B-Cell Differentiation Factor 2, B Cell B-Cell Differentiation Factor-2 B Cell Differentiation Factor 2 BSF-2 Hybridoma Growth Factor Growth Factor, Hybridoma IFN-beta 2 Plasmacytoma Growth Factor Growth Factor, Plasmacytoma Hepatocyte-Stimulating Factor Hepatocyte Stimulating Factor MGI-2 Myeloid Differentiation-Inducing Protein Differentiation-Inducing Protein, Myeloid Myeloid Differentiation Inducing Protein B-Cell Differentiation Factor B Cell Differentiation Factor Differentiation Factor, B-Cell Differentiation Factor, B Cell IL-6 Interferon beta-2 Interferon beta 2 beta-2, Interferon B Cell Stimulatory Factor-2 B Cell Stimulatory Factor 2

Below are MeSH descriptors whose meaning is more general than "Interleukin-6".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interleukins [D12.644.276.374.465]
Interleukin-6 [D12.644.276.374.465.224]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interleukins [D12.776.467.374.465]
Interleukin-6 [D12.776.467.374.465.202]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interleukins [D23.529.374.465]
Interleukin-6 [D23.529.374.465.224]

Below are MeSH descriptors whose meaning is related to "Interleukin-6".

Below are MeSH descriptors whose meaning is more specific than "Interleukin-6".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-6" by people in this website by year, and whether "Interleukin-6" was a major or minor topic of these publications.

Bar chart showing 113 publications over 27 distinct years, with a maximum of 11 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	2	2
1997	1	0	1
1999	1	0	1
2000	2	0	2
2002	0	3	3
2003	3	4	7
2004	0	3	3
2005	2	2	4
2006	1	7	8
2007	3	3	6
2008	2	5	7
2009	1	2	3
2010	0	1	1
2011	4	7	11
2012	3	6	9
2013	2	5	7
2014	1	4	5
2015	3	7	10
2016	1	2	3
2017	0	4	4
2018	1	0	1
2019	0	1	1
2020	1	2	3
2021	2	0	2
2022	0	4	4
2023	2	1	3
2024	0	2	2

Below are the most recent publications written about "Interleukin-6" by people in Profiles.

Brown JC, Ma C, Shi Q, Couture F, Kuebler P, Kumar P, Tan B, Krishnamurthi S, Chang V, Goldberg RM, O'Reilly EM, Shields AF, Meyerhardt JA. Inflammation, physical activity, and disease-free survival in stage III colon cancer: Cancer and Leukemia Group B-Southwest Oncology Group 80702 (Alliance). J Natl Cancer Inst. 2024 12 01; 116(12):2032-2039.

View in: PubMed
Grando K, Bessho S, Harrell K, Kyrylchuk K, Pantoja AM, Olubajo S, Albicoro FJ, Klein-Szanto A, T?kel ?. Bacterial amyloid curli activates the host unfolded protein response via IRE1a in the presence of HLA-B27. Gut Microbes. 2024 Jan-Dec; 16(1):2392877.

View in: PubMed
Wang QL, Ma C, Yuan C, Shi Q, Wolpin BM, Zhang Y, Fuchs CS, Meyer J, Zemla T, Cheng E, Kumthekar P, Guthrie KA, Couture F, Kuebler P, Kumar P, Tan B, Krishnamurthi S, Goldberg RM, Venook A, Blanke C, Shields AF, O'Reilly EM, Meyerhardt JA, Ng K. Plasma 25-Hydroxyvitamin D Levels and Survival in Stage III Colon Cancer: Findings from CALGB/SWOG 80702 (Alliance). Clin Cancer Res. 2023 07 14; 29(14):2621-2630.

View in: PubMed
Mahmood SBZ, Majid H, Arshad A, Niazali N, Kazi K, Aslam A, Ahmed S, Jamil B, Jafri L. Interleukin-6 (IL-6) as a Predictor of Clinical Outcomes in Patients with COVID-19. Clin Lab. 2023 Jun 01; 69(6).

View in: PubMed
Khan IA, Boyd BO, Chen AF, Cort?s-Penfield N, Myers TG, Brown TS, Suh GA, McGwin G, Ghanem ES, Fillingham YA. Utility of Diagnostic Tests Before Reimplantation in Patients Undergoing 2-Stage Revision Total Joint Arthroplasty: A Systematic Review and Meta-analysis. JBJS Rev. 2023 Mar 01; 11(3).

View in: PubMed
Cafardi J, Miller C, Terebelo H, Tewell C, Benzaquen S, Park D, Egan P, Lebovic D, Pettit K, Whitman E, Tremblay D, Feld J, Buckley S, Roman-Torres K, Smith J, Craig A, Mascarenhas J. Efficacy and Safety of Pacritinib vs Placebo for Patients With Severe COVID-19: A Phase 2 Randomized Clinical Trial. JAMA Netw Open. 2022 12 01; 5(12):e2242918.

View in: PubMed
Wanigatunga AA, Chiu V, Cai Y, Urbanek JK, Mitchell CM, Miller ER, Christenson RH, Rebuck H, Michos ED, Juraschek SP, Walston J, Xue QL, Bandeen-Roche K, Appel LJ, Schrack JA. Patterns of Daily Physical Movement, Chronic Inflammation, and Frailty Incidence. Med Sci Sports Exerc. 2023 02 01; 55(2):281-288.

View in: PubMed
Pol T, Hijazi Z, Lindb?ck J, Oldgren J, Alexander JH, Connolly SJ, Eikelboom JW, Ezekowitz MD, Granger CB, Lopes RD, Yusuf S, Siegbahn A, Wallentin L. Using multimarker screening to identify biomarkers associated with cardiovascular death in patients with atrial fibrillation. Cardiovasc Res. 2022 07 20; 118(9):2112-2123.

View in: PubMed
Dwi Astarini F, Ratnasari N, Wasityastuti W. Update on Non-Alcoholic Fatty Liver Disease-Associated Single Nucleotide Polymorphisms and Their Involvement in Liver Steatosis, Inflammation, and Fibrosis: A Narrative Review Iran Biomed J. 2022 07 01; 26(4):252-68.

View in: PubMed
Deaner JD, Jaffe GJ, Keenan RT, Carnago L, Grewal DS. Anti-Interleukin-6 Antibodies for Autoimmune Retinopathy with Macular Edema. Ophthalmol Retina. 2022 01; 6(1):91-93.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement