"CDC2 Protein Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL CYCLE. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of cyclin-dependent kinase 1 is achieved when it is fully dephosphorylated.
| Descriptor ID |
D016203
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.646.500.500.250 D08.811.913.696.620.682.700.646.500.984.500 D12.644.360.250.067.249 D12.644.360.250.580.500 D12.776.167.200.067.249 D12.776.167.200.580.500 D12.776.476.250.067.249 D12.776.476.250.580.500 D12.776.744.360
|
| Concept/Terms |
CDC2 Protein Kinase- CDC2 Protein Kinase
- Protein Kinase, CDC2
- Cdk1 Protein Kinase
- Protein Kinase, Cdk1
- cdk1 Kinase
- cdc2+ Protein
- Cyclin-Dependent Kinase 1
- Cyclin Dependent Kinase 1
p34cdc2 Protein- p34cdc2 Protein
- Protein p34cdc2
- p34cdc2, Protein
- Histone Kinase p34(cdc2)
|
Below are MeSH descriptors whose meaning is more general than "CDC2 Protein Kinase".
Below are MeSH descriptors whose meaning is more specific than "CDC2 Protein Kinase".
This graph shows the total number of publications written about "CDC2 Protein Kinase" by people in this website by year, and whether "CDC2 Protein Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "CDC2 Protein Kinase" by people in Profiles.
-
Corbi D, Sunder S, Weinreich M, Skokotas A, Johnson ES, Winter E. Multisite phosphorylation of the Sum1 transcriptional repressor by S-phase kinases controls exit from meiotic prophase in yeast. Mol Cell Biol. 2014 Jun; 34(12):2249-63.
-
Vecchione A, Baldassarre G, Ishii H, Nicoloso MS, Belletti B, Petrocca F, Zanesi N, Fong LY, Battista S, Guarnieri D, Baffa R, Alder H, Farber JL, Donovan PJ, Croce CM. Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development. Cancer Cell. 2007 Mar; 11(3):275-89.
-
Ujiki MB, Ding XZ, Salabat MR, Bentrem DJ, Golkar L, Milam B, Talamonti MS, Bell RH, Iwamura T, Adrian TE. Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest. Mol Cancer. 2006 Dec 29; 5:76.
-
Manes T, Zheng DQ, Tognin S, Woodard AS, Marchisio PC, Languino LR. Alpha(v)beta3 integrin expression up-regulates cdc2, which modulates cell migration. J Cell Biol. 2003 May 26; 161(4):817-26.
-
Wali A, Strayer DS. Infection with vaccinia virus alters regulation of cell cycle progression. DNA Cell Biol. 1999 Nov; 18(11):837-43.
-
Born TL, Frost JA, Sch?nthal A, Prendergast GC, Feramisco JR. c-Myc cooperates with activated Ras to induce the cdc2 promoter. Mol Cell Biol. 1994 Sep; 14(9):5710-8.