Hepatocyte Growth Factor

"Hepatocyte Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. Its receptor is PROTO-ONCOGENE PROTEINS C-MET.

Descriptor ID	D017228
MeSH Number(s)	D12.644.276.374.420 D12.776.467.374.420 D23.529.374.420
Concept/Terms	Hepatocyte Growth Factor Hepatocyte Growth Factor Factor, Hepatocyte Growth Growth Factor, Hepatocyte Scatter Factor Factor, Scatter Hepatopoietin Hepatopoietin A

Below are MeSH descriptors whose meaning is more general than "Hepatocyte Growth Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Hepatocyte Growth Factor [D12.644.276.374.420]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Hepatocyte Growth Factor [D12.776.467.374.420]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Hepatocyte Growth Factor [D23.529.374.420]

Below are MeSH descriptors whose meaning is related to "Hepatocyte Growth Factor".

Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Growth Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hepatocyte Growth Factor" by people in this website by year, and whether "Hepatocyte Growth Factor" was a major or minor topic of these publications.

Bar chart showing 15 publications over 14 distinct years, with a maximum of 2 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2001	1	0	1
2002	1	0	1
2003	0	1	1
2004	0	1	1
2006	1	0	1
2007	1	0	1
2009	0	1	1
2010	1	0	1
2012	0	1	1
2013	0	1	1
2015	1	0	1
2017	2	0	2
2024	0	1	1

Below are the most recent publications written about "Hepatocyte Growth Factor" by people in Profiles.

Guo ZF, Tongmuang N, Li C, Zhang C, Hu L, Capreri D, Zuo MX, Summer R, Sun J. Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice. JCI Insight. 2024 09 10; 9(17).

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Witt R, Weigand A, Boos AM, Cai A, Dippold D, Boccaccini AR, Schubert DW, Hardt M, Lange C, Arkudas A, Horch RE, Beier JP. Mesenchymal stem cells and myoblast differentiation under HGF and IGF-1 stimulation for 3D skeletal muscle tissue engineering. BMC Cell Biol. 2017 02 28; 18(1):15.

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Cheng H, Chua V, Liao C, Purwin TJ, Terai M, Kageyama K, Davies MA, Sato T, Aplin AE. Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma. Mol Cancer Ther. 2017 03; 16(3):516-528.

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Cheng H, Terai M, Kageyama K, Ozaki S, McCue PA, Sato T, Aplin AE. Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma. Cancer Res. 2015 Jul 01; 75(13):2737-48.

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Marchion DC, Bicaku E, Xiong Y, Bou Zgheib N, Al Sawah E, Stickles XB, Judson PL, Lopez AS, Cubitt CL, Gonzalez-Bosquet J, Wenham RM, Apte SM, Berglund A, Lancaster JM. A novel c-Met inhibitor, MK8033, synergizes with carboplatin plus paclitaxel to inhibit ovarian cancer cell growth. Oncol Rep. 2013 May; 29(5):2011-8.

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Gibney GT, Aziz SA, Camp RL, Conrad P, Schwartz BE, Chen CR, Kelly WK, Kluger HM. c-Met is a prognostic marker and potential therapeutic target in clear cell renal cell carcinoma. Ann Oncol. 2013 Feb; 24(2):343-349.

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Grugan KD, Miller CG, Yao Y, Michaylira CZ, Ohashi S, Klein-Szanto AJ, Diehl JA, Herlyn M, Han M, Nakagawa H, Rustgi AK. Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):11026-31.

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Zhang P, Baxter J, Vinod K, Tulenko TN, Di Muzio PJ. Endothelial differentiation of amniotic fluid-derived stem cells: synergism of biochemical and shear force stimuli. Stem Cells Dev. 2009 Nov; 18(9):1299-308.

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Matsumoto Y, Motoki T, Kubota S, Takigawa M, Tsubouchi H, Gohda E. Inhibition of tumor-stromal interaction through HGF/Met signaling by valproic acid. Biochem Biophys Res Commun. 2008 Feb 01; 366(1):110-6.

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Tate A, Isotani S, Bradley MJ, Sikes RA, Davis R, Chung LW, Edlund M. Met-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells. BMC Cancer. 2006 Jul 25; 6:197.

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