Interferons

"Interferons" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.

Descriptor ID	D007372
MeSH Number(s)	D12.644.276.374.440 D12.776.467.374.440 D23.529.374.440
Concept/Terms	Interferons Interferons Interferon

Below are MeSH descriptors whose meaning is more general than "Interferons".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interferons [D12.644.276.374.440]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interferons [D12.776.467.374.440]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interferons [D23.529.374.440]

Below are MeSH descriptors whose meaning is related to "Interferons".

Below are MeSH descriptors whose meaning is more specific than "Interferons".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interferons" by people in this website by year, and whether "Interferons" was a major or minor topic of these publications.

Bar chart showing 42 publications over 25 distinct years, with a maximum of 4 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	2	0	2
1998	0	1	1
1999	0	1	1
2000	0	1	1
2001	1	0	1
2002	0	1	1
2004	0	2	2
2005	0	1	1
2007	2	1	3
2008	1	1	2
2009	0	1	1
2010	1	1	2
2011	0	1	1
2012	0	1	1
2013	1	1	2
2014	2	0	2
2017	0	1	1
2018	0	2	2
2019	1	1	2
2020	2	2	4
2021	1	1	2
2022	0	2	2
2023	1	2	3
2024	0	1	1

Below are the most recent publications written about "Interferons" by people in Profiles.

Murayama T, Nakayama J, Jiang X, Miyata K, Morris AD, Cai KQ, Prasad RM, Ma X, Efimov A, Belani N, Gerstein ER, Tan Y, Zhou Y, Kim W, Maruyama R, Campbell KS, Chen L, Yang Y, Balachandran S, Ca?adas I. Targeting DHX9 Triggers Tumor-Intrinsic Interferon Response and Replication Stress in Small Cell Lung Cancer. Cancer Discov. 2024 Mar 01; 14(3):468-491.

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Sharma M, Chakravarty D, Hussain A, Zalavadia A, Burrows A, Rayman P, Sharma N, Kenyon LC, Bergmann C, Sen GC, Das Sarma J. Ifit2 restricts murine coronavirus spread to the spinal cord white matter and its associated myelin pathology. J Virol. 2023 08 31; 97(8):e0074923.

View in: PubMed
Meyer SE. Context is key for FLT3-ITD. Blood. 2023 03 23; 141(12):1373-1374.

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Montoya B, Knudson CJ, Melo-Silva CR, Tang L, Kafle S, Sigal LJ. Resistance To Poxvirus Lethality Does Not Require the Necroptosis Proteins RIPK3 or MLKL. J Virol. 2023 02 28; 97(2):e0194522.

View in: PubMed
Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG. DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 11 28; 226(11):2030-2036.

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Yi M, Niu M, Wu Y, Ge H, Jiao D, Zhu S, Zhang J, Yan Y, Zhou P, Chu Q, Wu K. Combination of oral STING agonist MSA-2 and anti-TGF-?/PD-L1 bispecific antibody YM101: a novel immune cocktail therapy for non-inflamed tumors. J Hematol Oncol. 2022 10 08; 15(1):142.

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Song IH, Kim YA, Heo SH, Bang WS, Park HS, Choi YH, Lee H, Seo JH, Cho Y, Jung SW, Kim HJ, Ahn SH, Lee HJ, Gong G. The Association of Estrogen Receptor Activity, Interferon Signaling, and MHC Class I Expression in Breast Cancer. Cancer Res Treat. 2022 Oct; 54(4):1111-1120.

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Domeier PP, Rahman ZSM. Regulation of B Cell Responses in SLE by Three Classes of Interferons. Int J Mol Sci. 2021 Sep 28; 22(19).

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Das Sarma J, Burrows A, Rayman P, Hwang MH, Kundu S, Sharma N, Bergmann C, Sen GC. Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection. PLoS Pathog. 2020 11; 16(11):e1009034.

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Piera-Velazquez S, Mendoza FA, Addya S, Pomante D, Jimenez SA. Increased expression of interferon regulated and antiviral response genes in CD31+/CD102+ lung microvascular endothelial cells from systemic sclerosis patients with end-stage interstitial lung disease. Clin Exp Rheumatol. 2021 Nov-Dec; 39(6):1298-1306.

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