Interleukin 1 Receptor Antagonist Protein
"Interleukin 1 Receptor Antagonist Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA.
| Descriptor ID |
D053590
|
| MeSH Number(s) |
D12.644.276.374.460 D12.776.467.374.460 D23.529.374.460
|
| Concept/Terms |
Interleukin 1 Receptor Antagonist Protein- Interleukin 1 Receptor Antagonist Protein
- IL1 Febrile Inhibitor
- Febrile Inhibitor, IL1
- IL-1Ra
- Urine-Derived IL1 Inhibitor
- IL1 Inhibitor, Urine-Derived
- Urine Derived IL1 Inhibitor
- IL-1 Inhibitor, Urine
- IL 1 Inhibitor, Urine
- Urine IL-1 Inhibitor
- Interleukin 1 Inhibitor, Urine
|
Below are MeSH descriptors whose meaning is more general than "Interleukin 1 Receptor Antagonist Protein".
Below are MeSH descriptors whose meaning is more specific than "Interleukin 1 Receptor Antagonist Protein".
This graph shows the total number of publications written about "Interleukin 1 Receptor Antagonist Protein" by people in this website by year, and whether "Interleukin 1 Receptor Antagonist Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin 1 Receptor Antagonist Protein" by people in Profiles.
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Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, Bassiri H, Behrens EM, Ferris A, Kernan KF, Schulert GS, Seo P, Son MBF, Tremoulet AH, Yeung RSM, Mudano AS, Turner AS, Karp DR, Mehta JJ. American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 2. Arthritis Rheumatol. 2021 Apr; 73(4):e13-e29.
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Dove ML, Jaggi P, Kelleman M, Abuali M, Ang JY, Ballan W, Basu SK, Campbell MJ, Chikkabyrappa SM, Choueiter NF, Clouser KN, Corwin D, Edwards A, Gertz SJ, Ghassemzadeh R, Jarrah RJ, Katz SE, Knutson SM, Kuebler JD, Lighter J, Mikesell C, Mongkolrattanothai K, Morton T, Nakra NA, Olivero R, Osborne CM, Panesar LE, Parsons S, Patel RM, Schuette J, Thacker D, Tremoulet AH, Vidwan NK, Oster ME. Multisystem Inflammatory Syndrome in Children: Survey of Protocols for Early Hospital Evaluation and Management. J Pediatr. 2021 02; 229:33-40.
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Soriano A, Verecchia E, Afeltra A, Landolfi R, Manna R. IL-1? biological treatment of familial Mediterranean fever. Clin Rev Allergy Immunol. 2013 Aug; 45(1):117-30.
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Fain JN, Tichansky DS, Madan AK. Most of the interleukin 1 receptor antagonist, cathepsin S, macrophage migration inhibitory factor, nerve growth factor, and interleukin 18 release by explants of human adipose tissue is by the non-fat cells, not by the adipocytes. Metabolism. 2006 Aug; 55(8):1113-21.
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Lee KM, Park SK, Hamajima N, Tajima K, Choi JY, Noh DY, Ahn SH, Yoo KY, Hirvonen A, Kang D. Genetic polymorphisms of interleukin-1 beta (IL-1B) and IL-1 receptor antagonist (IL-1RN) and breast cancer risk in Korean women. Breast Cancer Res Treat. 2006 Mar; 96(2):197-202.
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Rider LG, Artlett CM, Foster CB, Ahmed A, Neeman T, Chanock SJ, Jimenez SA, Miller FW. Polymorphisms in the IL-1 receptor antagonist gene VNTR are possible risk factors for juvenile idiopathic inflammatory myopathies. Clin Exp Immunol. 2000 Jul; 121(1):47-52.