"Leukotriene D4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990)
| Descriptor ID |
D017998
|
| MeSH Number(s) |
D10.251.355.255.100.450.855.461 D10.251.355.310.166.887.855.461 D23.469.050.175.450.725.415
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Leukotriene D4".
Below are MeSH descriptors whose meaning is more specific than "Leukotriene D4".
This graph shows the total number of publications written about "Leukotriene D4" by people in this website by year, and whether "Leukotriene D4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Leukotriene D4" by people in Profiles.
-
Hoopes C. Invited commentary. Ann Thorac Surg. 2006 Sep; 82(3):1088-9.
-
Naik S, Billington CK, Pascual RM, Deshpande DA, Stefano FP, Kohout TA, Eckman DM, Benovic JL, Penn RB. Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling. J Biol Chem. 2005 Mar 11; 280(10):8722-32.
-
Ruck LM, Rizzo CA, Anthes JC, Eckel S, Egan RW, Cuss FM, Hey JA. Synergistic antiallergic activity of combined histamine H1- and cysteinyl leukotriene1-receptor blockade in human bronchus. Life Sci. 2001 May 11; 68(25):2825-34.
-
Schwartz JI, Margolskee DJ, Bjornsson TD, Williams VC, Hsieh JY, Lin CC, Rogers JD. Oral pharmacokinetics and food interaction of the leukotriene D4 receptor antagonist verlukast. Br J Clin Pharmacol. 1993 Nov; 36(5):464-6.