"Endothelin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
| Descriptor ID |
D019332
|
| MeSH Number(s) |
D12.644.276.400.225 D12.776.467.400.225 D23.529.400.225
|
| Concept/Terms |
Proendothelin (1-38)- Proendothelin (1-38)
- Big Endothelin
- Big Endothelin-1
- Big Endothelin 1
- Endothelin-1, Big
- Endothelin, Big
Preproendothelin-1- Preproendothelin-1
- Preproendothelin 1
- Preproendothelin
- Proendothelin-1 Precursor
- Precursor, Proendothelin-1
- Proendothelin 1 Precursor
|
Below are MeSH descriptors whose meaning is more general than "Endothelin-1".
Below are MeSH descriptors whose meaning is more specific than "Endothelin-1".
This graph shows the total number of publications written about "Endothelin-1" by people in this website by year, and whether "Endothelin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 3 | 0 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 1 | 1 | 2 |
| 2024 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Endothelin-1" by people in Profiles.
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Gonsalves AM, Baker SE, Jacob DW, Harper JL, Manrique-Acevedo CM, Limberg JK. Effect of endothelin-1 on the blood pressure response to acute hypoxia and hyperoxia in healthy young men. Physiol Rep. 2024 09; 12(17):e70004.
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Limberg JK, Baker SE, Ott EP, Jacob DW, Scruggs ZM, Harper JL, Manrique-Acevedo CM. Endothelin-1 receptor blockade does not alter the sympathetic and hemodynamic response to acute intermittent hypoxia in men. J Appl Physiol (1985). 2022 10 01; 133(4):867-875.
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Limberg JK, Baker SE, Petersen-Jones HG, Guo W, Huang A, Jensen MD, Singh P. Endothelin-1 as a novel target for the prevention of metabolic dysfunction with intermittent hypoxia in male participants. Am J Physiol Regul Integr Comp Physiol. 2022 09 01; 323(3):R351-R362.
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Kerr AL, Curtis MT, Dominguez M, Viola V. Poststroke exercise is as effective as skilled rehabilitation: Effects in young and aged mice. Behav Neurosci. 2018 Dec; 132(6):604-613.
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Wermuth PJ, Li Z, Mendoza FA, Jimenez SA. Stimulation of Transforming Growth Factor-?1-Induced Endothelial-To-Mesenchymal Transition and Tissue Fibrosis by Endothelin-1 (ET-1): A Novel Profibrotic Effect of ET-1. PLoS One. 2016; 11(9):e0161988.
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Camoretti-Mercado B, Pauer SH, Yong HM, Smith DC, Deshpande DA, An SS, Liggett SB. Pleiotropic Effects of Bitter Taste Receptors on [Ca2+]i Mobilization, Hyperpolarization, and Relaxation of Human Airway Smooth Muscle Cells. PLoS One. 2015; 10(6):e0131582.
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Sen A, Most P, Peppel K. Induction of microRNA-138 by pro-inflammatory cytokines causes endothelial cell dysfunction. FEBS Lett. 2014 Mar 18; 588(6):906-14.
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Deliu E, Brailoiu GC, Mallilankaraman K, Wang H, Madesh M, Undieh AS, Koch WJ, Brailoiu E. Intracellular endothelin type B receptor-driven Ca2+ signal elicits nitric oxide production in endothelial cells. J Biol Chem. 2012 Nov 30; 287(49):41023-31.
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Ha NH, Nair VS, Reddy DN, Mudvari P, Ohshiro K, Ghanta KS, Pakala SB, Li DQ, Costa L, Lipton A, Badwe RA, Fuqua S, Wallon M, Prendergast GC, Kumar R. Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes. Cancer Res. 2011 Dec 01; 71(23):7259-69.
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DeLoach S, Huan Y, Daskalakis C, Falkner B. Endothelin-1 response to glucose and insulin among African Americans. J Am Soc Hypertens. 2010 Sep-Oct; 4(5):227-35.