Endothelins

"Endothelins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.

Descriptor ID	D016232
MeSH Number(s)	D12.644.276.400 D12.776.467.400 D23.529.400
Concept/Terms	Endothelins Endothelins Endothelium-Derived Vasoconstrictor Factors Vasoconstrictor Factors, Endothelium-Derived Endothelin

Below are MeSH descriptors whose meaning is more general than "Endothelins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Endothelins [D12.644.276.400]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Endothelins [D12.776.467.400]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Endothelins [D23.529.400]

Below are MeSH descriptors whose meaning is more specific than "Endothelins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Endothelins" by people in this website by year, and whether "Endothelins" was a major or minor topic of these publications.

Bar chart showing 11 publications over 8 distinct years, with a maximum of 3 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	2	0	2
1998	1	0	1
2000	1	0	1
2002	1	2	3
2010	0	1	1
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "Endothelins" by people in Profiles.

Tummala S, Kuczmarski AV, Del Vecchio AR, Schwab AI, Edwards DG, Wenner MM. Antecubital venous endothelial ETB receptor protein expression is preserved with aging in men. Am J Physiol Heart Circ Physiol. 2024 01 01; 326(1):H110-H115.

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Limberg JK, Baker SE, Ott EP, Jacob DW, Scruggs ZM, Harper JL, Manrique-Acevedo CM. Endothelin-1 receptor blockade does not alter the sympathetic and hemodynamic response to acute intermittent hypoxia in men. J Appl Physiol (1985). 2022 10 01; 133(4):867-875.

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Derrett-Smith EC, Dooley A, Khan K, Shi-wen X, Abraham D, Denton CP. Systemic vasculopathy with altered vasoreactivity in a transgenic mouse model of scleroderma. Arthritis Res Ther. 2010; 12(2):R69.

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Chow M, Dumont AS, Kassell NF. Endothelin receptor antagonists and cerebral vasospasm: an update. Neurosurgery. 2002 Dec; 51(6):1333-41; discussion 1342.

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Muslu A, Islek I, Gok F, Aliyazicioglu Y, Dagdemir A, Dundaroz R, Kucukoduk S, Sakarcan A. Endothelin levels in Henoch-Schonlein purpura. Pediatr Nephrol. 2002 Nov; 17(11):920-5.

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Wang H, Eto M, Steers WD, Somlyo AP, Somlyo AV. RhoA-mediated Ca2+ sensitization in erectile function. J Biol Chem. 2002 Aug 23; 277(34):30614-21.

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Petkova SB, Tanowitz HB, Magazine HI, Factor SM, Chan J, Pestell RG, Bouzahzah B, Douglas SA, Shtutin V, Morris SA, Tsang E, Weiss LM, Christ GJ, Wittner M, Huang H. Myocardial expression of endothelin-1 in murine Trypanosoma cruzi infection. Cardiovasc Pathol. 2000 Sep-Oct; 9(5):257-65.

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Inman SR, Osgood RW, Plott WK, Hubosky SG, Burns TE, Lewis RM. Urinary excretion of endothelin is elevated during hypothermic perfusion preservation in kidneys subjected to preretrieval warm ischemic injury. Transplant Proc. 2000 Jun; 32(4):802-3.

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Petkova SB, Ashton A, Bouzahzah B, Huang H, Pestell RG, Tanowitz HB. Cell cycle molecules and diseases of the cardiovascular system. Front Biosci. 2000 Apr 01; 5:D452-60.

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Hotter G, Pi F, Sanz C, Peralta C, Prats N, Gelpi E, Badosa F, Fern?ndez-Cruz L, Rosell?-Catafau J. Endothelin mediated nitric oxide effects in ischemia--reperfusion associated with pancreas transplantation. Dig Dis Sci. 1998 Dec; 43(12):2627-33.

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