"Endothelins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
| Descriptor ID |
D016232
|
| MeSH Number(s) |
D12.644.276.400 D12.776.467.400 D23.529.400
|
| Concept/Terms |
Endothelins- Endothelins
- Endothelium-Derived Vasoconstrictor Factors
- Vasoconstrictor Factors, Endothelium-Derived
- Endothelin
|
Below are MeSH descriptors whose meaning is more general than "Endothelins".
Below are MeSH descriptors whose meaning is more specific than "Endothelins".
This graph shows the total number of publications written about "Endothelins" by people in this website by year, and whether "Endothelins" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Endothelins" by people in Profiles.
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Tummala S, Kuczmarski AV, Del Vecchio AR, Schwab AI, Edwards DG, Wenner MM. Antecubital venous endothelial ETB receptor protein expression is preserved with aging in men. Am J Physiol Heart Circ Physiol. 2024 01 01; 326(1):H110-H115.
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Limberg JK, Baker SE, Ott EP, Jacob DW, Scruggs ZM, Harper JL, Manrique-Acevedo CM. Endothelin-1 receptor blockade does not alter the sympathetic and hemodynamic response to acute intermittent hypoxia in men. J Appl Physiol (1985). 2022 10 01; 133(4):867-875.
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Derrett-Smith EC, Dooley A, Khan K, Shi-wen X, Abraham D, Denton CP. Systemic vasculopathy with altered vasoreactivity in a transgenic mouse model of scleroderma. Arthritis Res Ther. 2010; 12(2):R69.
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Muslu A, Islek I, Gok F, Aliyazicioglu Y, Dagdemir A, Dundaroz R, Kucukoduk S, Sakarcan A. Endothelin levels in Henoch-Schonlein purpura. Pediatr Nephrol. 2002 Nov; 17(11):920-5.
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Wang H, Eto M, Steers WD, Somlyo AP, Somlyo AV. RhoA-mediated Ca2+ sensitization in erectile function. J Biol Chem. 2002 Aug 23; 277(34):30614-21.
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Hotter G, Pi F, Sanz C, Peralta C, Prats N, Gelpi E, Badosa F, Fern?ndez-Cruz L, Rosell?-Catafau J. Endothelin mediated nitric oxide effects in ischemia--reperfusion associated with pancreas transplantation. Dig Dis Sci. 1998 Dec; 43(12):2627-33.
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Peralta C, Hotter G, Closa D, Pi F, Badosa F, Gelp? E, Rosell?-Catafau J. Nitric oxide enhances endothelin production in pancreas transplantation. Pancreas. 1997 May; 14(4):369-72.
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Salzman SK, Acosta R, Beck G, Madden J, Boxer B, Ohlstein EH. Spinal endothelin content is elevated after moderate local trauma in the rat to levels associated with locomotor dysfunction after intrathecal injection. J Neurotrauma. 1996 Feb; 13(2):93-101.
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Bax WA, Aghai Z, van Tricht CL, Wassenaar C, Saxena PR. Different endothelin receptors involved in endothelin-1- and sarafotoxin S6B-induced contractions of the human isolated coronary artery. Br J Pharmacol. 1994 Dec; 113(4):1471-9.
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Erickson-Lamy K, Korbmacher C, Schuman JS, Nathanson JA. Effect of endothelin on outflow facility and accommodation in the monkey eye in vivo. Invest Ophthalmol Vis Sci. 1991 Mar; 32(3):492-5.