Receptor, Ciliary Neurotrophic Factor
"Receptor, Ciliary Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors for CILIARY NEUROTROPHIC FACTOR. They are heterotrimeric proteins formed by the association of the CILIARY NEUROTROPHIC FACTOR RECEPTOR ALPHA SUBUNIT with the LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR GP130. Although the receptor regulates neuronal development, it is structurally similar to the cytokine receptor for INTERLEUKIN-6; (RECEPTORS, INTERLEUKIN-6).
| Descriptor ID |
D020801
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| MeSH Number(s) |
D12.776.543.750.750.400.550.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Receptor, Ciliary Neurotrophic Factor".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Ciliary Neurotrophic Factor".
This graph shows the total number of publications written about "Receptor, Ciliary Neurotrophic Factor" by people in this website by year, and whether "Receptor, Ciliary Neurotrophic Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, Ciliary Neurotrophic Factor" by people in Profiles.
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Tossetta G, Fantone S, Busilacchi EM, Di Simone N, Giannubilo SR, Scambia G, Giordano A, Marzioni D. Modulation of matrix metalloproteases by ciliary neurotrophic factor in human placental development. Cell Tissue Res. 2022 Oct; 390(1):113-129.
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Miknyoczki SJ, Lang D, Huang L, Klein-Szanto AJ, Dionne CA, Ruggeri BA. Neurotrophins and Trk receptors in human pancreatic ductal adenocarcinoma: expression patterns and effects on in vitro invasive behavior. Int J Cancer. 1999 May 05; 81(3):417-27.
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Economides AN, Ravetch JV, Yancopoulos GD, Stahl N. Designer cytokines: targeting actions to cells of choice. Science. 1995 Nov 24; 270(5240):1351-3.
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Klein R, Smeyne RJ, Wurst W, Long LK, Auerbach BA, Joyner AL, Barbacid M. Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death. Cell. 1993 Oct 08; 75(1):113-22.