Receptor, trkB

"Receptor, trkB" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; neurotrophin 4 and neurotrophin 5. It is widely expressed in nervous tissue and plays a role in mediating the effects of neurotrophins on growth and differentiation of neuronal cells.

Descriptor ID	D020813
MeSH Number(s)	D08.811.913.696.620.682.725.400.700 D12.776.543.750.630.498 D12.776.543.750.750.400.550.600
Concept/Terms	Receptor, trkB Receptor, trkB BDNF Receptor Receptor, BDNF trkB Receptor Receptor, Neurotrophic Tyrosine Kinase Type 2 NTRK2 Receptor Receptor, NTRK2 Brain Derived Neurotrophic Factor Receptor Neurotrophic Tyrosine Kinase Receptor Type 2 trkB(gp145) Protein Neurotrophic Factor, Brain-Derived, Receptor

Below are MeSH descriptors whose meaning is more general than "Receptor, trkB".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
Receptor, trkB [D08.811.913.696.620.682.725.400.700]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
Receptor, trkB [D12.776.543.750.630.498]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Growth Factor [D12.776.543.750.750.400]
Receptors, Nerve Growth Factor [D12.776.543.750.750.400.550]
Receptor, trkB [D12.776.543.750.750.400.550.600]

Below are MeSH descriptors whose meaning is related to "Receptor, trkB".

Below are MeSH descriptors whose meaning is more specific than "Receptor, trkB".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptor, trkB" by people in this website by year, and whether "Receptor, trkB" was a major or minor topic of these publications.

Bar chart showing 10 publications over 9 distinct years, with a maximum of 2 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2009	0	1	1
2012	0	1	1
2014	0	1	1
2015	0	1	1
2019	0	1	1
2020	1	1	2
2021	1	0	1
2023	0	1	1

Below are the most recent publications written about "Receptor, trkB" by people in Profiles.

Lin R, Mallick AB, Wang ZX, Brown SA, Lu B, Jiang W. Identification of dual STRN-NTRK2 rearrangements in a high grade sarcoma, with good clinical response to first-line larotrectinib therapy. Diagn Pathol. 2023 Oct 21; 18(1):116.

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Gupta P, Singh A, Gupta RK. Pacinian Corpuscles in Pancreas: Possible Clinical Implications. Pancreas. 2021 07 01; 50(6):e56-e57.

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Paris AJ, Hayer KE, Oved JH, Avgousti DC, Toulmin SA, Zepp JA, Zacharias WJ, Katzen JB, Basil MC, Kremp MM, Slamowitz AR, Jayachandran S, Sivakumar A, Dai N, Wang P, Frank DB, Eisenlohr LC, Cantu E, Beers MF, Weitzman MD, Morrisey EE, Worthen GS. STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury. Nat Cell Biol. 2020 10; 22(10):1197-1210.

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Lasota J, Chlopek M, Lamoureux J, Christiansen J, Kowalik A, Wasag B, Felisiak-Golabek A, Agaimy A, Biernat W, Canzonieri V, Centonze G, Chmielik E, Daum O, Dubov? M, Dziuba I, Goertz S, G?zdz S, Guttmejer-Nasierowska A, Haglund C, Halon A, Hartmann A, Inaguma S, Izycka-Swieszewska E, Kaczorowski M, Kita P, Kolos M, Kopczynski J, Michal M, Milione M, Okon K, Peksa R, Pyzlak M, Ristim?ki A, Rys J, Szostak B, Szpor J, Szumilo J, Teresinski L, Waloszczyk P, Wejman J, Wesolowski W, Miettinen M. Colonic Adenocarcinomas Harboring NTRK Fusion Genes: A Clinicopathologic and Molecular Genetic Study of 16 Cases and Review of the Literature. Am J Surg Pathol. 2020 02; 44(2):162-173.

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Singh A, Mohanty I, Singh J, Rattan S. BDNF augments rat internal anal sphincter smooth muscle tone via RhoA/ROCK signaling and nonadrenergic noncholinergic relaxation via increased NO release. Am J Physiol Gastrointest Liver Physiol. 2020 01 01; 318(1):G23-G33.

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Williams SN, Undieh AS. Dopamine-sensitive signaling mediators modulate psychostimulant-induced ultrasonic vocalization behavior in rats. Behav Brain Res. 2016 Jan 01; 296:1-6.

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Tian J, Tep C, Benedick A, Saidi N, Ryu JC, Kim ML, Sadasivan S, Oberdick J, Smeyne R, Zhu MX, Yoon SO. p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1. J Biol Chem. 2014 Nov 07; 289(45):31458-72.

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Milman T, Hu DN, McCormick SA, Eagle RC, Crawford JB, Chin K, Shields CL, Shields JA, Char DH, Finger PT. Expression of neurotrophin receptors by retinoinvasive uveal melanoma. Melanoma Res. 2012 Apr; 22(2):164-8.

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Williams SN, Undieh AS. Brain-derived neurotrophic factor signaling modulates cocaine induction of reward-associated ultrasonic vocalization in rats. J Pharmacol Exp Ther. 2010 Feb; 332(2):463-8.

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Nibu K, Li G, Zhang X, Rawson NE, Restrepo D, Kaga K, Lowry LD, Keane WM, Rothstein JL. Olfactory neuron-specific expression of NeuroD in mouse and human nasal mucosa. Cell Tissue Res. 1999 Dec; 298(3):405-14.

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