Cytokine Receptor gp130

"Cytokine Receptor gp130" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cytokine receptor that contains extracellular FIBRONECTIN TYPE III DOMAINS which mediate its function through the formation of oligomeric complexes with itself, or with a variety of CYTOKINE RECEPTORS. It does not bind IL-6, but activates JANUS KINASES and STAT3 TRANSCRIPTION FACTOR.

Descriptor ID	D050822
MeSH Number(s)	D12.776.543.750.705.852.420.400.500 D12.776.543.750.705.852.420.560.249 D12.776.543.750.705.852.555.600.500 D12.776.543.750.705.852.583.500 D12.776.543.750.750.400.550.250.500
Concept/Terms	Cytokine Receptor gp130 Cytokine Receptor gp130 gp130, Cytokine Receptor IL-6 Receptor Signal Transducer gp130 IL6ST gp130 gp130 Transducing Protein Signal Transducer gp130 gp130, Signal Transducer Antigens, CD130 gp130 Signal Transducer Signal Transducer, gp130 gp130 IL-6 Family Receptor gp130 IL 6 Family Receptor IL-6 Family Receptor gp130 CD130 Antigens Interleukin-6 Receptor Subunit Beta Interleukin 6 Receptor Subunit Beta Signal-Transducing Receptor gp130 Receptor gp130, Signal-Transducing Signal Transducing Receptor gp130 gp130, Signal-Transducing Receptor Soluble Glycoprotein 130 Soluble Glycoprotein 130 Glycoprotein 130, Soluble Soluble gp130 gp130, Soluble sgp130

Below are MeSH descriptors whose meaning is more general than "Cytokine Receptor gp130".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Interleukin [D12.776.543.750.705.852.420]
Receptors, Interleukin-6 [D12.776.543.750.705.852.420.400]
Cytokine Receptor gp130 [D12.776.543.750.705.852.420.400.500]
Receptors, Interleukin-11 [D12.776.543.750.705.852.420.560]
Cytokine Receptor gp130 [D12.776.543.750.705.852.420.560.249]
Receptors, Oncostatin M [D12.776.543.750.705.852.555]
Receptors, Oncostatin M, Type II [D12.776.543.750.705.852.555.600]
Cytokine Receptor gp130 [D12.776.543.750.705.852.555.600.500]
Receptors, OSM-LIF [D12.776.543.750.705.852.583]
Cytokine Receptor gp130 [D12.776.543.750.705.852.583.500]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Growth Factor [D12.776.543.750.750.400]
Receptors, Nerve Growth Factor [D12.776.543.750.750.400.550]
Receptor, Ciliary Neurotrophic Factor [D12.776.543.750.750.400.550.250]
Cytokine Receptor gp130 [D12.776.543.750.750.400.550.250.500]

Below are MeSH descriptors whose meaning is related to "Cytokine Receptor gp130".

Below are MeSH descriptors whose meaning is more specific than "Cytokine Receptor gp130".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cytokine Receptor gp130" by people in this website by year, and whether "Cytokine Receptor gp130" was a major or minor topic of these publications.

Bar chart showing 7 publications over 6 distinct years, with a maximum of 2 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2010	0	1	1
2011	1	1	2
2014	0	1	1
2021	0	1	1
2022	1	0	1

Below are the most recent publications written about "Cytokine Receptor gp130" by people in Profiles.

Liu NQ, Lin Y, Li L, Lu J, Geng D, Zhang J, Jashashvili T, Buser Z, Magallanes J, Tassey J, Shkhyan R, Sarkar A, Lopez N, Lee S, Lee Y, Wang L, Petrigliano FA, Van Handel B, Lyons K, Evseenko D. gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes. Commun Biol. 2022 01 17; 5(1):64.

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Geethadevi A, Nair A, Parashar D, Ku Z, Xiong W, Deng H, Li Y, George J, McAllister DM, Sun Y, Kadamberi IP, Gupta P, Dwinell MB, Bradley WH, Rader JS, Rui H, Schwabe RF, Zhang N, Pradeep S, An Z, Chaluvally-Raghavan P. Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth. Cancer Res. 2021 10 15; 81(20):5336-5352.

View in: PubMed
Nagayama Y, Braun GS, Jakobs CM, Maruta Y, van Roeyen CR, Klinkhammer BM, Boor P, Villa L, Raffetseder U, Trautwein C, G?rtz D, M?ller-Newen G, Ostendorf T, Floege J. Gp130-dependent signaling in the podocyte. Am J Physiol Renal Physiol. 2014 Aug 01; 307(3):F346-55.

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Laskiewicz L, Jiang Z, Altieri DC, Languino LR. The search for a better prostate cancer biomarker. J Urol. 2011 Nov; 186(5):1758-9.

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Li J, Zhao Q, Xing W, Feng J, Wu H, Li H, Ge M, Tian K, Li X, Zhou J, Liu B, Zhang L, Zheng Y, Han ZC. Interleukin-27 enhances the production of tumour necrosis factor-a and interferon-? by bone marrow T lymphocytes in aplastic anaemia. Br J Haematol. 2011 Jun; 153(6):764-72.

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Li JP, Wu H, Xing W, Yang SG, Lu SH, Du WT, Yu JX, Chen F, Zhang L, Han ZC. Interleukin-27 as a negative regulator of human neutrophil function. Scand J Immunol. 2010 Oct; 72(4):284-92.

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Falco GD, Neri LM, Falco MD, Bellan C, Yu Z, Luca AD, Leoncini L, Giordano A. Cdk9, a member of the cdc2-like family of kinases, binds to gp130, the receptor of the IL-6 family of cytokines. Oncogene. 2002 Oct 24; 21(49):7464-70.

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Economides AN, Ravetch JV, Yancopoulos GD, Stahl N. Designer cytokines: targeting actions to cells of choice. Science. 1995 Nov 24; 270(5240):1351-3.

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