T-Cell Acute Lymphocytic Leukemia Protein 1
"T-Cell Acute Lymphocytic Leukemia Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic helix-loop-helix transcription factor that plays a critical role in HEMATOPOIESIS and as a positive regulator in the differentiation of ERYTHROID CELLS. Chromosome translocations involving the TAL-1 gene are associated with T-CELL ACUTE LYMPHOCYTIC LEUKEMIA.
| Descriptor ID |
D000073942
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| MeSH Number(s) |
D12.776.260.103.829 D12.776.624.664.700.960 D12.776.930.125.829
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "T-Cell Acute Lymphocytic Leukemia Protein 1".
Below are MeSH descriptors whose meaning is more specific than "T-Cell Acute Lymphocytic Leukemia Protein 1".
This graph shows the total number of publications written about "T-Cell Acute Lymphocytic Leukemia Protein 1" by people in this website by year, and whether "T-Cell Acute Lymphocytic Leukemia Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "T-Cell Acute Lymphocytic Leukemia Protein 1" by people in Profiles.
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Zeuner A, Eramo A, Testa U, Felli N, Pelosi E, Mariani G, Srinivasula SM, Alnemri ES, Condorelli G, Peschle C, De Maria R. Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1. Cell Death Differ. 2003 Aug; 10(8):905-13.
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Hosler GA, Bash RO, Bai X, Jain V, Scheuermann RH. Development and validation of a quantitative polymerase chain reaction assay to evaluate minimal residual disease for T-cell acute lymphoblastic leukemia and follicular lymphoma. Am J Pathol. 1999 Apr; 154(4):1023-35.
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Chen Q, Yang CY, Tsan JT, Xia Y, Ragab AH, Peiper SC, Carroll A, Baer R. Coding sequences of the tal-1 gene are disrupted by chromosome translocation in human T cell leukemia. J Exp Med. 1990 Nov 01; 172(5):1403-8.