Below are the most recent publications written about "Dopaminergic Neurons" by people in Profiles.
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Rocha SM, Kirkley KS, Chatterjee D, Aboellail TA, Smeyne RJ, Tjalkens RB. Microglia-specific knock-out of NF-?B/IKK2 increases the accumulation of misfolded a-synuclein through the inhibition of p62/sequestosome-1-dependent autophagy in the rotenone model of Parkinson's disease. Glia. 2023 09; 71(9):2154-2179.
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Rocha SM, Bantle CM, Aboellail T, Chatterjee D, Smeyne RJ, Tjalkens RB. Rotenone induces regionally distinct a-synuclein protein aggregation and activation of glia prior to loss of dopaminergic neurons in C57Bl/6 mice. Neurobiol Dis. 2022 06 01; 167:105685.
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Bantle CM, Rocha SM, French CT, Phillips AT, Tran K, Olson KE, Bass TA, Aboellail T, Smeyne RJ, Tjalkens RB. Astrocyte inflammatory signaling mediates a-synuclein aggregation and dopaminergic neuronal loss following viral encephalitis. Exp Neurol. 2021 12; 346:113845.
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Oakes HV, McWethy D, Ketchem S, Tran L, Phillips K, Oakley L, Smeyne RJ, Pond BB. Effect of Chronic Methylphenidate Treatment in a Female Experimental Model of Parkinsonism. Neurotox Res. 2021 Jun; 39(3):667-676.
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Kostuk EW, Cai J, Iacovitti L. Subregional differences in astrocytes underlie selective neurodegeneration or protection in Parkinson's disease models in culture. Glia. 2019 08; 67(8):1542-1557.
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Kostuk EW, Cai J, Iacovitti L. Regional microglia are transcriptionally distinct but similarly exacerbate neurodegeneration in a culture model of Parkinson's disease. J Neuroinflammation. 2018 May 11; 15(1):139.
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Yoon KW, Yang HS, Kim YM, Kim Y, Kang S, Sun W, Naik UP, Parise LV, Choi EJ. CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1. Sci Rep. 2017 09 22; 7(1):12178.
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Smeyne RJ, Breckenridge CB, Beck M, Jiao Y, Butt MT, Wolf JC, Zadory D, Minnema DJ, Sturgess NC, Travis KZ, Cook AR, Smith LL, Botham PA. Assessment of the Effects of MPTP and Paraquat on Dopaminergic Neurons and Microglia in the Substantia Nigra Pars Compacta of C57BL/6 Mice. PLoS One. 2016; 11(10):e0164094.
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Monti DA, Zabrecky G, Kremens D, Liang TW, Wintering NA, Cai J, Wei X, Bazzan AJ, Zhong L, Bowen B, Intenzo CM, Iacovitti L, Newberg AB. N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Preliminary Clinical and Cell Line Data. PLoS One. 2016; 11(6):e0157602.
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Smeyne M, Sladen P, Jiao Y, Dragatsis I, Smeyne RJ. HIF1a is necessary for exercise-induced neuroprotection while HIF2a is needed for dopaminergic neuron survival in the substantia nigra pars compacta. Neuroscience. 2015 Jun 04; 295:23-38.