"Dithiothreitol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols.
| Descriptor ID |
D004229
|
| MeSH Number(s) |
D02.033.800.196 D02.886.740.224 D09.853.196
|
| Concept/Terms |
Dithiothreitol- Dithiothreitol
- Cleland's Reagent
- Clelands Reagent
- Reagent, Cleland's
- Cleland Reagent
- Reagent, Cleland
|
Below are MeSH descriptors whose meaning is more general than "Dithiothreitol".
Below are MeSH descriptors whose meaning is more specific than "Dithiothreitol".
This graph shows the total number of publications written about "Dithiothreitol" by people in this website by year, and whether "Dithiothreitol" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dithiothreitol" by people in Profiles.
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Motlekar N, Diamond SL, Napper AD. Evaluation of an orthogonal pooling strategy for rapid high-throughput screening of proteases. Assay Drug Dev Technol. 2008 Jun; 6(3):395-405.
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Myers MC, Napper AD, Motlekar N, Shah PP, Chiu CH, Beavers MP, Diamond SL, Huryn DM, Smith AB. Identification and characterization of 3-substituted pyrazolyl esters as alternate substrates for cathepsin B: the confounding effects of DTT and cysteine in biological assays. Bioorg Med Chem Lett. 2007 Sep 01; 17(17):4761-6.
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Thakur ML, DeFulvio J, Richard MD, Park CH. Technetium-99m labeled monoclonal antibodies: evaluation of reducing agents. Int J Rad Appl Instrum B. 1991; 18(2):227-33.
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Thakur ML, DeFulvio J. Radiolabeled antibodies specific for human blood elements. Prog Clin Biol Res. 1990; 355:281-92.
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Reginato AM, Shapiro IM, Lash JW, Jimenez SA. Type X collagen alterations in rachitic chick epiphyseal growth cartilage. J Biol Chem. 1988 Jul 15; 263(20):9938-45.
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Jimenez SA, Yankowski R, Reginato AM. Quantitative analysis of type X-collagen biosynthesis by embryonic-chick sternal cartilage. Biochem J. 1986 Jan 15; 233(2):357-67.
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Sampson PM, Jimenez SA, Bashey RI. Isolation and partial characterization of proteoglycans from sheep lung parenchyma. Biochim Biophys Acta. 1979 Nov 15; 588(1):129-41.
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Jimenez SA, Bashey RI. Solubilization of bovine heart-value collagen. Biochem J. 1978 Jul 01; 173(1):337-40.