"Factor V" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.
Descriptor ID |
D005165
|
MeSH Number(s) |
D12.776.124.125.300 D23.119.300
|
Concept/Terms |
Factor V- Factor V
- Factor Five
- Five, Factor
- AC Globulin
- Blood Coagulation Factor V
- Factor Pi
- Proaccelerin
- Factor 5
- Coagulation Factor V
- Factor V, Coagulation
|
Below are MeSH descriptors whose meaning is more general than "Factor V".
Below are MeSH descriptors whose meaning is more specific than "Factor V".
This graph shows the total number of publications written about "Factor V" by people in this website by year, and whether "Factor V" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 |
1998 | 2 | 0 | 2 |
1999 | 0 | 1 | 1 |
2000 | 4 | 1 | 5 |
2001 | 0 | 2 | 2 |
2002 | 1 | 0 | 1 |
2003 | 1 | 1 | 2 |
2005 | 3 | 3 | 6 |
2008 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
2015 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Factor V" by people in Profiles.
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Weiss MY, Kuriyan AE. Acute Monocular Vision Loss in a Young Adult. JAMA Ophthalmol. 2018 Mar 01; 136(3):297-298.
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Patounakis G, Bergh E, Forman EJ, Tao X, Lonczak A, Franasiak JM, Treff N, Scott RT. Multiple thrombophilic single nucleotide polymorphisms lack a significant effect on outcomes in fresh IVF cycles: an analysis of 1717 patients. J Assist Reprod Genet. 2016 Jan; 33(1):67-73.
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Kang KA, Ren Y, Sharma VR, Peiper SC. Near real-time immuno-optical sensor for diagnosing single point mutation: a model system: sensor for factor V Leiden diagnosis. Biosens Bioelectron. 2009 May 15; 24(9):2785-90.
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Slamon N, Krueger LJ, Edelson M, Glutting JJ, Rittenhouse D. A retrospective study of the factors associated with hypercoagulability in the pediatric patients at a tertiary care children's hospital. Pediatr Crit Care Med. 2008 Sep; 9(5):511-6.
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Schlachterman A, Schuettrumpf J, Liu JH, Furlan Freguia C, Freguia CF, Toso R, Poncz M, Camire RM, Arruda VR. Factor V Leiden improves in vivo hemostasis in murine hemophilia models. J Thromb Haemost. 2005 Dec; 3(12):2730-7.
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Schuettrumpf J, Zou J, Zhang Y, Schlachterman A, Liu YL, Edmonson S, Xiao W, Arruda VR. The inhibitory effects of anticoagulation on in vivo gene transfer by adeno-associated viral or adenoviral vectors. Mol Ther. 2006 Jan; 13(1):88-97.
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Preston FE, Jennings I, Kitchen DP, Woods TA, Kitchen S. Variability in factor V:C assays in UK National External Quality Assessment Scheme surveys: there is a need for an international standard. Blood Coagul Fibrinolysis. 2005 Oct; 16(7):529-31.
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Dunn SP, Tsai A, Griffin G, Toth S, Casas-Melley AT, Falkenstein KP, Marando CA, Krueger LJ. Liver transplantation as definitive treatment for a factor V Leiden mutation. J Pediatr. 2005 Mar; 146(3):418-22.
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Jennings I, Kitchen S, Woods TA, Preston FE. Multilaboratory testing in thrombophilia through the United Kingdom National External Quality Assessment Scheme (Blood Coagulation) Quality Assurance Program. Semin Thromb Hemost. 2005 Feb; 31(1):66-72.
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Keller MA. Molecular diagnostic testing for inherited thrombophilia using Invader. Methods Mol Med. 2005; 114:107-19.