Fibronectins

"Fibronectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.

Descriptor ID	D005353
MeSH Number(s)	D12.776.377.715.390 D12.776.395.550.350 D12.776.543.550.350 D12.776.860.300.450
Concept/Terms	Fibronectins Fibronectins Opsonic alpha(2)SB Glycoprotein Opsonic Glycoprotein Glycoprotein, Opsonic LETS Proteins Proteins, LETS alpha 2-Surface Binding Glycoprotein alpha 2 Surface Binding Glycoprotein Fibronectin Cold-Insoluble Globulins Cold Insoluble Globulins Globulins, Cold-Insoluble

Below are MeSH descriptors whose meaning is more general than "Fibronectins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Globulins [D12.776.377]
Serum Globulins [D12.776.377.715]
Fibronectins [D12.776.377.715.390]
Glycoproteins [D12.776.395]
Membrane Glycoproteins [D12.776.395.550]
Fibronectins [D12.776.395.550.350]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Fibronectins [D12.776.543.550.350]
Scleroproteins [D12.776.860]
Extracellular Matrix Proteins [D12.776.860.300]
Fibronectins [D12.776.860.300.450]

Below are MeSH descriptors whose meaning is related to "Fibronectins".

Below are MeSH descriptors whose meaning is more specific than "Fibronectins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fibronectins" by people in this website by year, and whether "Fibronectins" was a major or minor topic of these publications.

Bar chart showing 159 publications over 28 distinct years, with a maximum of 17 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	0	2
1997	1	2	3
1999	2	3	5
2000	1	4	5
2001	0	3	3
2002	3	5	8
2003	2	3	5
2004	6	6	12
2005	9	8	17
2006	5	3	8
2007	11	5	16
2008	2	1	3
2009	2	6	8
2010	3	3	6
2011	3	3	6
2012	0	4	4
2013	2	2	4
2014	1	2	3
2015	4	2	6
2016	3	5	8
2017	1	2	3
2018	0	2	2
2019	2	3	5
2020	2	3	5
2021	0	2	2
2022	4	2	6
2023	1	1	2
2024	1	1	2

Below are the most recent publications written about "Fibronectins" by people in Profiles.

Ramaraj PK, Pol M, Scinto SL, Jia X, Fox JM. Covalent Attachment of Functional Proteins to Microfiber Surfaces via a General Strategy for Site-Selective Tetrazine Ligation. ACS Appl Mater Interfaces. 2024 Nov 20; 16(46):63195-63206.

View in: PubMed
Arriagada C, Lin E, Schonning M, Astrof S. Mesodermal fibronectin controls cell shape, polarity, and mechanotransduction in the second heart field during cardiac outflow tract development. Dev Cell. 2025 01 06; 60(1):62-84.e7.

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Cohen AJ, Nikbakht N, Uitto J. Keloid Disorder: Genetic Basis, Gene Expression Profiles, and Immunological Modulation of the Fibrotic Processes in the Skin. Cold Spring Harb Perspect Biol. 2023 07 05; 15(7).

View in: PubMed
Melamed S, Zaffryar-Eilot S, Nadjar-Boger E, Aviram R, Zhao H, Yaseen-Badarne W, Kalev-Altman R, Sela-Donenfeld D, Lewinson O, Astrof S, Hasson P, Wolfenson H. Initiation of fibronectin fibrillogenesis is an enzyme-dependent process. Cell Rep. 2023 05 30; 42(5):112473.

View in: PubMed
Adulla A, Patel U, Ashok A, Katiyar P, Kaulakis M, Kritikos AE, Pillai S, Lee H, Lindner E, Rhee DJ, Singh N. a-Synuclein modulates fibronectin expression in the trabecular meshwork independent of TGF?2. Exp Eye Res. 2023 01; 226:109351.

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Menko AS, Walker JL. The Pro-Fibrotic Response to Lens Injury Is Signaled in a PI3K Isoform-Specific Manner. Biomolecules. 2022 08 25; 12(9).

View in: PubMed
Tomer D, Arriagada C, Munshi S, Alexander BE, French B, Vedula P, Caorsi V, House A, Guvendiren M, Kashina A, Schwarzbauer JE, Astrof S. A new mechanism of fibronectin fibril assembly revealed by live imaging and super-resolution microscopy. J Cell Sci. 2022 08 15; 135(16).

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Dwi Astarini F, Ratnasari N, Wasityastuti W. Update on Non-Alcoholic Fatty Liver Disease-Associated Single Nucleotide Polymorphisms and Their Involvement in Liver Steatosis, Inflammation, and Fibrosis: A Narrative Review Iran Biomed J. 2022 07 01; 26(4):252-68.

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MacDonald WW, Swaminathan SS, Heo JY, Castillejos A, Hsueh J, Liu BJ, Jo D, Du A, Lee H, Kang MH, Rhee DJ. Effect of SPARC Suppression in Mice, Perfused Human Anterior Segments, and Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2022 06 01; 63(6):8.

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Beksa? B, Gleason L, Baik S, Ringe JM, Porcu P, Nikbakht N. Dermal fibroblasts promote cancer cell proliferation and exhibit fibronectin overexpression in early mycosis fungoides. J Dermatol Sci. 2022 Apr; 106(1):53-60.

View in: PubMed

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