Immunoglobulin Constant Regions
"Immunoglobulin Constant Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The domains of the immunoglobulin molecules that are invariable in their amino acid sequence within any class or subclass of immunoglobulin. They confer biological as well as structural functions to immunoglobulins. One each on both the light chains and the heavy chains comprises the C-terminus half of the IMMUNOGLOBULIN FAB FRAGMENT and two or three of them make up the rest of the heavy chains (all of the IMMUNOGLOBULIN FC FRAGMENT)
| Descriptor ID |
D007127
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| MeSH Number(s) |
D12.776.124.486.485.538 D12.776.124.790.651.538 D12.776.377.715.548.538
|
| Concept/Terms |
Immunoglobulin Constant Regions- Immunoglobulin Constant Regions
- Constant Regions, Immunoglobulin
- Constant Region, Ig
- Immunoglobulin Constant Region
- Constant Region, Immunoglobulin
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Constant Regions".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Constant Regions".
This graph shows the total number of publications written about "Immunoglobulin Constant Regions" by people in this website by year, and whether "Immunoglobulin Constant Regions" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin Constant Regions" by people in Profiles.
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Depiero A, Kaminski DA, Halsey JF, Briles D, Burrows PD, Hostoffer RW. Immunologic compensation in a patient with a large IgH constant region deletion. J Allergy Clin Immunol. 2001 Jun; 107(6):1051-5.
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Schuler W, Schuler A, Lennon GG, Bosma GC, Bosma MJ. Transcription of unrearranged antigen receptor genes in scid mice. EMBO J. 1988 Jul; 7(7):2019-24.
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Sun LK, Curtis P, Rakowicz-Szulczynska E, Ghrayeb J, Chang N, Morrison SL, Koprowski H. Chimeric antibody with human constant regions and mouse variable regions directed against carcinoma-associated antigen 17-1A. Proc Natl Acad Sci U S A. 1987 Jan; 84(1):214-8.
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Sun LK, Curtis P, Rakowicz-Szulczynska E, Ghrayeb J, Morrison SL, Chang N, Koprowski H. Chimeric antibodies with 17-1A-derived variable and human constant regions. Hybridoma. 1986 Jul; 5 Suppl 1:S17-20.
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Marks R, Bosma MJ. Truncated mu (mu') chains in murine IgM. Evidence that mu' chains lack variable regions. J Exp Med. 1985 Dec 01; 162(6):1862-77.