"Paraproteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered.
| Descriptor ID |
D010266
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| MeSH Number(s) |
D12.776.124.486.485.900 D12.776.124.790.651.900 D12.776.377.715.548.900
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Paraproteins".
Below are MeSH descriptors whose meaning is more specific than "Paraproteins".
This graph shows the total number of publications written about "Paraproteins" by people in this website by year, and whether "Paraproteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Paraproteins" by people in Profiles.
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Hortin GL, Stapp RT, Thapa SB, Grajales-Cruz AF. Problematic Proteins: A Patient with a High Paraprotein Concentration. Clin Chem. 2024 Jul 05; 70(7):905-908.
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Ahmed S, Afzal N, Jafri L, Khan MD, Khan MQA, Iqbal S, Abbas G, Imran K, Ali U, Siddiqui I. Reporting Practices of Serum Protein Electrophoresis in Pakistan - a Multicenter Survey. Clin Lab. 2024 Feb 01; 70(2).
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Webster GF, Matsuoka LY, Burchmore D. The association of potentially lethal neurologic syndromes with scleromyxedema (papular mucinosis). J Am Acad Dermatol. 1993 Jan; 28(1):105-8.
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Ilyas AA, Cook SD, Dalakas MC, Mithen FA. Anti-MAG IgM paraproteins from some patients with polyneuropathy associated with IgM paraproteinemia also react with sulfatide. J Neuroimmunol. 1992 Mar; 37(1-2):85-92.
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Ilyas AA, Willison HJ, Dalakas MC, Whitaker JN, Quarles RH. Identification and characterization of gangliosides reacting with IgM paraproteins in three patients with neuropathy associated with biclonal gammopathy. J Neurochem. 1988 Sep; 51(3):851-8.
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Elder G, Dalakas MC, Papadopoulos N, Sever JL. Peripheral neuropathy and light chain myeloma: case report. Neurology. 1987 Jan; 37(1):173-4.
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Ilyas AA, Dalakas MC, Brady RO, Quarles RH. Sulfated glucuronyl glycolipids reacting with anti-myelin-associated glycoprotein monoclonal antibodies including IgM paraproteins in neuropathy: species distribution and partial characterization of epitopes. Brain Res. 1986 Oct 15; 385(1):1-9.
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Ilyas AA, Quarles RH, Dalakas MC, Fishman PH, Brady RO. Monoclonal IgM in a patient with paraproteinemic polyneuropathy binds to gangliosides containing disialosyl groups. Ann Neurol. 1985 Dec; 18(6):655-9.
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Ilyas AA, Quarles RH, Dalakas MC, Brady RO. Polyneuropathy with monoclonal gammopathy: glycolipids are frequently antigens for IgM paraproteins. Proc Natl Acad Sci U S A. 1985 Oct; 82(19):6697-700.
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Dalakas MC, Papadopoulos NM. Paraproteins in the spinal fluid of patients with paraproteinemic polyneuropathies. Ann Neurol. 1984 Jun; 15(6):590-3.