"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
|
| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 2 | 1 | 3 |
| 2003 | 1 | 3 | 4 |
| 2004 | 1 | 3 | 4 |
| 2005 | 4 | 2 | 6 |
| 2006 | 1 | 5 | 6 |
| 2007 | 1 | 4 | 5 |
| 2008 | 4 | 2 | 6 |
| 2009 | 2 | 7 | 9 |
| 2010 | 4 | 2 | 6 |
| 2011 | 3 | 7 | 10 |
| 2012 | 3 | 1 | 4 |
| 2013 | 1 | 3 | 4 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Insulin" by people in Profiles.
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Morrione A, Belfiore A. Obesity, Diabetes, and Cancer: The Role of the Insulin/IGF Axis; Mechanisms and Clinical Implications. Biomolecules. 2022 Apr 20; 12(5).
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Vella V, Giuliano M, Nicolosi ML, Majorana MG, Marc MA, Muoio MG, Morrione A, Maggiolini M, Lappano R, De Francesco EM, Belfiore A. DDR1 Affects Metabolic Reprogramming in Breast Cancer Cells by Cross-Talking to the Insulin/IGF System. Biomolecules. 2021 06 22; 11(7).
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Evans L, London JW, Palchuk MB. Assessing real-world medication data completeness. J Biomed Inform. 2021 07; 119:103847.
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Miller AJ, Bingaman SS, Mehay D, Medina D, Arnold AC. Angiotensin-(1-7) Improves Integrated Cardiometabolic Function in Aged Mice. Int J Mol Sci. 2020 Jul 20; 21(14).
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Ostan R, Monti D, Mari D, Arosio B, Gentilini D, Ferri E, Passarino G, De Rango F, D'Aquila P, Mariotti S, Pasquali R, Fanelli F, Bucci L, Franceschi C, Vitale G. Heterogeneity of Thyroid Function and Impact of Peripheral Thyroxine Deiodination in Centenarians and Semi-Supercentenarians: Association With Functional Status and Mortality. J Gerontol A Biol Sci Med Sci. 2019 05 16; 74(6):802-810.
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Xiao D, Zhu L, Edirisinghe I, Fareed J, Brailovsky Y, Burton-Freeman B. Attenuation of Postmeal Metabolic Indices with Red Raspberries in Individuals at Risk for Diabetes: A Randomized Controlled Trial. Obesity (Silver Spring). 2019 04; 27(4):542-550.
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Mathieu C, Dandona P, Gillard P, Senior P, Hasslacher C, Araki E, Lind M, Bain SC, Jabbour S, Arya N, Hansen L, Thorén F, Langkilde AM. Efficacy and Safety of Dapagliflozin in Patients With Inadequately Controlled Type 1 Diabetes (the DEPICT-2 Study): 24-Week Results From a Randomized Controlled Trial. Diabetes Care. 2018 09; 41(9):1938-1946.
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Daniel R, Villuri S, Furlong K. Management of hyperglycemia in the neurosurgery patient. Hosp Pract (1995). 2017 Oct; 45(4):150-157.
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Palmieri EM, Menga A, Lebrun A, Hooper DC, Butterfield DA, Mazzone M, Castegna A. Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells. Antioxid Redox Signal. 2017 03 10; 26(8):351-363.
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Winters B, Plymate S, Zeliadt SB, Holt S, Zhang X, Hu E, Lin DW, Morrissey C, Wooldridge B, Gore JL, Porter MP, Wright JL. Metformin effects on biochemical recurrence and metabolic signaling in the prostate. Prostate. 2015 Nov; 75(15):1694-703.