Interferons

"Interferons" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.

Descriptor ID	D007372
MeSH Number(s)	D12.644.276.374.440 D12.776.467.374.440 D23.529.374.440
Concept/Terms	Interferons Interferons Interferon

Below are MeSH descriptors whose meaning is more general than "Interferons".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interferons [D12.644.276.374.440]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interferons [D12.776.467.374.440]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interferons [D23.529.374.440]

Below are MeSH descriptors whose meaning is related to "Interferons".

Below are MeSH descriptors whose meaning is more specific than "Interferons".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interferons" by people in this website by year, and whether "Interferons" was a major or minor topic of these publications.

Bar chart showing 33 publications over 22 distinct years, with a maximum of 3 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	2	0	2
1998	0	1	1
1999	0	1	1
2000	0	1	1
2001	1	0	1
2002	0	1	1
2004	0	2	2
2005	0	1	1
2007	2	1	3
2008	1	1	2
2009	0	1	1
2010	1	1	2
2011	0	1	1
2012	0	1	1
2013	1	1	2
2014	2	0	2
2019	1	0	1
2020	1	1	2
2021	1	1	2
2022	0	2	2
2023	1	0	1

Below are the most recent publications written about "Interferons" by people in Profiles.

Meyer SE. Context is key for FLT3-ITD. Blood. 2023 Mar 23; 141(12):1373-1374.

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Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG. DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 11 28; 226(11):2030-2036.

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Yi M, Niu M, Wu Y, Ge H, Jiao D, Zhu S, Zhang J, Yan Y, Zhou P, Chu Q, Wu K. Combination of oral STING agonist MSA-2 and anti-TGF-?/PD-L1 bispecific antibody YM101: a novel immune cocktail therapy for non-inflamed tumors. J Hematol Oncol. 2022 10 08; 15(1):142.

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Song IH, Kim YA, Heo SH, Bang WS, Park HS, Choi YH, Lee H, Seo JH, Cho Y, Jung SW, Kim HJ, Ahn SH, Lee HJ, Gong G. The Association of Estrogen Receptor Activity, Interferon Signaling, and MHC Class I Expression in Breast Cancer. Cancer Res Treat. 2022 Oct; 54(4):1111-1120.

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Domeier PP, Rahman ZSM. Regulation of B Cell Responses in SLE by Three Classes of Interferons. Int J Mol Sci. 2021 Sep 28; 22(19).

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Das Sarma J, Burrows A, Rayman P, Hwang MH, Kundu S, Sharma N, Bergmann C, Sen GC. Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection. PLoS Pathog. 2020 11; 16(11):e1009034.

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Kim H, Gunter-Rahman F, McGrath JA, Lee E, de Jesus AA, Targoff IN, Huang Y, O'Hanlon TP, Tsai WL, Gadina M, Miller FW, Goldbach-Mansky R, Rider LG. Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathies. Arthritis Res Ther. 2020 04 06; 22(1):69.

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Milora KA, Rall GF. Interferon Control of Neurotropic Viral Infections. Trends Immunol. 2019 09; 40(9):842-856.

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Cavanaugh SE, Holmgren AM, Rall GF. Homeostatic interferon expression in neurons is sufficient for early control of viral infection. J Neuroimmunol. 2015 Feb 15; 279:11-9.

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Pfeffer LM, Li K, Fleckenstein JF, Marion TN, Diament J, Yang CH, Pfeffer SR, Fan M, Handorf E, Handorf CR. An interferon response gene signature is associated with the therapeutic response of hepatitis C patients. PLoS One. 2014; 9(8):e104202.

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