S100 Proteins

"S100 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of highly acidic calcium-binding proteins found in large concentration in the brain and believed to be glial in origin. They are also found in other organs in the body. They have in common the EF-hand motif (EF HAND MOTIFS) found on a number of calcium binding proteins. The name of this family derives from the property of being soluble in a 100% saturated ammonium sulfate solution.

Descriptor ID	D009418
MeSH Number(s)	D12.776.157.125.750 D12.776.631.655
Concept/Terms	S100 Proteins S100 Proteins Nerve Tissue Protein S 100 S100 Protein Family Antigen S 100 S-100 Protein S 100 Protein

Below are MeSH descriptors whose meaning is more general than "S100 Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Calcium-Binding Proteins [D12.776.157.125]
S100 Proteins [D12.776.157.125.750]
Nerve Tissue Proteins [D12.776.631]
S100 Proteins [D12.776.631.655]

Below are MeSH descriptors whose meaning is related to "S100 Proteins".

Below are MeSH descriptors whose meaning is more specific than "S100 Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "S100 Proteins" by people in this website by year, and whether "S100 Proteins" was a major or minor topic of these publications.

Bar chart showing 90 publications over 26 distinct years, with a maximum of 6 publications in 2005 and 2007 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	2	2
1997	0	1	1
1998	0	1	1
1999	0	5	5
2000	0	3	3
2001	0	4	4
2002	1	3	4
2003	0	3	3
2004	0	2	2
2005	1	5	6
2006	4	1	5
2007	4	2	6
2008	1	3	4
2009	2	0	2
2010	3	0	3
2011	2	2	4
2012	2	2	4
2013	4	1	5
2014	2	4	6
2015	4	1	5
2016	2	1	3
2018	2	2	4
2019	1	2	3
2022	0	1	1
2024	3	0	3
2025	1	0	1

Below are the most recent publications written about "S100 Proteins" by people in Profiles.

Nouri Z, Biglari S, Tabatabaiefar MA, Vahidnezhad F, Hozhabrpour A, March ME, Margolis DJ, Gudjonsson JE, Hakonarson H, Vahidnezhad H. Filaggrinopathies-FLG/FLG2: Diagnostic Complexities and Immunotherapy. J Invest Dermatol. 2025 Jul; 145(7):1622-1632.

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Kehr D, Ritterhoff J, Glaser M, Jarosch L, Salazar RE, Spaich K, Varadi K, Birkenstock J, Egger M, Gao E, Koch WJ, Sauter M, Freichel M, Katus HA, Frey N, Jungmann A, Busch C, Mather PJ, Ruhparwar A, Busch M, V?lkers M, Wade RC, Most P. S100A1ct: A Synthetic Peptide Derived From S100A1 Protein Improves Cardiac Performance and Survival in Preclinical Heart Failure Models. Circulation. 2025 Feb 25; 151(8):548-565.

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Seitz A, Busch M, Kroemer J, Schneider A, Simon S, Jungmann A, Katus HA, Most P, Ritterhoff J. S100A1's single cysteine is an indispensable redox switch for the protection against diastolic calcium waves in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2024 07 01; 327(1):H000.

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Noll D, Kehr D, Most P, Ritterhoff J. S100A1: a promising therapeutic target for heart failure. Expert Opin Ther Targets. 2024 Apr; 28(4):233-236.

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Kaczorowski M, Chlopek M, Kruczak A, Rys J, Lasota J, Miettinen M. PRAME Expression in Cancer. A Systematic Immunohistochemical Study of >5800 Epithelial and Nonepithelial Tumors. Am J Surg Pathol. 2022 11 01; 46(11):1467-1476.

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Katz MG, Gubara SM, Hadas Y, Weber T, Kumar A, Eliyahu E, Bridges CR, Fargnoli AS. Effects of genetic transfection on calcium cycling pathways mediated by double-stranded adeno-associated virus in postinfarction remodeling. J Thorac Cardiovasc Surg. 2020 05; 159(5):1809-1819.e3.

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McKey K, Zhang PJL, Shields CL, Lally SE, Eagle RC, Milman T. Orbital Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma Masquerading as Pleomorphic Lipoma: A Diagnostic Challenge. Ophthalmic Plast Reconstr Surg. 2019 May/Jun; 35(3):e76-e80.

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Elhaji Y, Sasseville D, Pratt M, Asai Y, Matheson K, McLean WHI, Hull PR. Filaggrin gene loss-of-function mutations constitute a factor in patients with multiple contact allergies. Contact Dermatitis. 2019 Jun; 80(6):354-358.

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Goldbach AR, Hava S, Caroline D, Zhao X, Bains A, Pascarella S. Rosai-Dorfman disease of the breast: A potential marker of systemic disease. Breast J. 2019 01; 25(1):134-137.

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Hulshof L, Hack DP, Hasnoe QCJ, Dontje B, Jakasa I, Riethm?ller C, McLean WHI, van Aalderen WMC, Van't Land B, Kezic S, Sprikkelman AB, Middelkamp-Hup MA. A minimally invasive tool to study immune response and skin barrier in children with atopic dermatitis. Br J Dermatol. 2019 03; 180(3):621-630.

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