Platelet-Derived Growth Factor

"Platelet-Derived Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.

Descriptor ID	D010982
MeSH Number(s)	D12.644.276.910 D12.776.124.625 D12.776.467.910 D23.529.910
Concept/Terms	Platelet-Derived Growth Factor Platelet-Derived Growth Factor Factor, Platelet-Derived Growth Growth Factor, Platelet-Derived Platelet Derived Growth Factor

Below are MeSH descriptors whose meaning is more general than "Platelet-Derived Growth Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Platelet-Derived Growth Factor [D12.644.276.910]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Platelet-Derived Growth Factor [D12.776.124.625]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Platelet-Derived Growth Factor [D12.776.467.910]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Platelet-Derived Growth Factor [D23.529.910]

Below are MeSH descriptors whose meaning is related to "Platelet-Derived Growth Factor".

Below are MeSH descriptors whose meaning is more specific than "Platelet-Derived Growth Factor".

Platelet-Derived Growth Factor
Proto-Oncogene Proteins c-sis

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Platelet-Derived Growth Factor" by people in this website by year, and whether "Platelet-Derived Growth Factor" was a major or minor topic of these publications.

Bar chart showing 38 publications over 19 distinct years, with a maximum of 4 publications in 1999 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
1997	1	0	1
1998	1	2	3
1999	0	4	4
2000	0	1	1
2001	0	1	1
2002	1	2	3
2003	0	3	3
2004	0	2	2
2005	1	2	3
2007	2	1	3
2008	1	0	1
2010	1	0	1
2011	3	1	4
2012	0	2	2
2013	1	0	1
2016	1	0	1
2017	1	0	1
2022	0	2	2

Below are the most recent publications written about "Platelet-Derived Growth Factor" by people in Profiles.

Jia T, Xu T, Smeets B, Buhl EM, Moeller MJ, Floege J, Klinkhammer BM, Boor P. The Role of Platelet-Derived Growth Factor in Focal Segmental Glomerulosclerosis. J Am Soc Nephrol. 2023 02 01; 34(2):241-257.

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Hernandez-Lara MA, Yadav SK, Shah SD, Okumura M, Yokoyama Y, Penn RB, Kambayashi T, Deshpande DA. Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma. Int J Mol Sci. 2022 Oct 06; 23(19).

View in: PubMed
Klinkhammer BM, Floege J, Boor P. PDGF in organ fibrosis. Mol Aspects Med. 2018 08; 62:44-62.

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Buhl EM, Djudjaj S, Babickova J, Klinkhammer BM, Folestad E, Borkham-Kamphorst E, Weiskirchen R, Hudkins K, Alpers CE, Eriksson U, Floege J, Boor P. The role of PDGF-D in healthy and fibrotic kidneys. Kidney Int. 2016 Apr; 89(4):848-61.

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Miettinen M, Lasota J. Gastrointestinal stromal tumors. Gastroenterol Clin North Am. 2013 Jun; 42(2):399-415.

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Kim JI, Urban M, Young GD, Eto M. Reciprocal regulation controlling the expression of CPI-17, a specific inhibitor protein for the myosin light chain phosphatase in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2012 Jul 1; 303(1):C58-68.

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Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM. CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One. 2012; 7(2):e30562.

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Tsou PS, Talia NN, Pinney AJ, Kendzicky A, Piera-Velazquez S, Jimenez SA, Seibold JR, Phillips K, Koch AE. Effect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts. Arthritis Rheum. 2012 Jun; 64(6):1978-89.

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Pera T, Sami R, Zaagsma J, Meurs H. TAK1 plays a major role in growth factor-induced phenotypic modulation of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2011 Nov; 301(5):L822-8.

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Huang M, Satchell L, Duhadaway JB, Prendergast GC, Laury-Kleintop LD. RhoB links PDGF signaling to cell migration by coordinating activation and localization of Cdc42 and Rac. J Cell Biochem. 2011 Jun; 112(6):1572-84.

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