Parathyroid Hormone-Related Protein

"Parathyroid Hormone-Related Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A ubiquitously expressed, secreted protein with bone resorption and renal calcium reabsorption activities that are similar to PARATHYROID HORMONE. It does not circulate in appreciable amounts in normal subjects, but rather exerts its biological actions locally. Overexpression of parathyroid hormone-related protein by tumor cells results in humoral calcemia of malignancy.

Descriptor ID	D044162
MeSH Number(s)	D06.472.699.591 D12.644.276.908 D12.644.548.588 D12.776.467.890 D23.529.890
Concept/Terms	Parathyroid Hormone-Related Protein Parathyroid Hormone-Related Protein Hormone-Related Protein, Parathyroid Parathyroid Hormone Related Protein Parathyroid Hormone-Like Protein Parathyroid Hormone Like Protein Parathyroid Hormone-Related Peptide Parathyroid Hormone Related Peptide PTHrP Tumor Hypercalcemic Factor Hypercalcemic Factor, Tumor Hypercalcemic Hormone of Malignancy PTH Like Tumor Factor PTH-Like Protein PTH Like Protein Parathyroid Hormone Like Tumor Factor PTH-Related Peptide PTH Related Peptide

Below are MeSH descriptors whose meaning is more general than "Parathyroid Hormone-Related Protein".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Parathyroid Hormone-Related Protein [D06.472.699.591]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Parathyroid Hormone-Related Protein [D12.644.276.908]
Peptide Hormones [D12.644.548]
Parathyroid Hormone-Related Protein [D12.644.548.588]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Parathyroid Hormone-Related Protein [D12.776.467.890]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Parathyroid Hormone-Related Protein [D23.529.890]

Below are MeSH descriptors whose meaning is related to "Parathyroid Hormone-Related Protein".

Below are MeSH descriptors whose meaning is more specific than "Parathyroid Hormone-Related Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Parathyroid Hormone-Related Protein" by people in this website by year, and whether "Parathyroid Hormone-Related Protein" was a major or minor topic of these publications.

Bar chart showing 12 publications over 10 distinct years, with a maximum of 2 publications in 2002 and 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2002	0	2	2
2004	0	1	1
2005	1	0	1
2008	1	1	2
2009	0	1	1
2013	0	1	1
2014	0	1	1
2015	1	0	1
2018	1	0	1

Below are the most recent publications written about "Parathyroid Hormone-Related Protein" by people in Profiles.

Tran TH, Utama FE, Sato T, Peck AR, Langenheim JF, Udhane SS, Sun Y, Liu C, Girondo MA, Kovatich AJ, Hooke JA, Shriver CD, Hu H, Palazzo JP, Bibbo M, Auer PW, Flister MJ, Hyslop T, Mitchell EP, Chervoneva I, Rui H. Loss of Nuclear Localized Parathyroid Hormone-Related Protein in Primary Breast Cancer Predicts Poor Clinical Outcome and Correlates with Suppressed Stat5 Signaling. Clin Cancer Res. 2018 12 15; 24(24):6355-6366.

View in: PubMed
Mills TA, Orloff M, Domingo-Vidal M, Cotzia P, Birbe RC, Draganova-Tacheva R, Martinez Cantarin MP, Tuluc M, Martinez-Outschoorn U. Parathyroid Hormone-Related Peptide-Linked Hypercalcemia in a Melanoma Patient Treated With Ipilimumab: Hormone Source and Clinical and Metabolic Correlates. Semin Oncol. 2015 Dec; 42(6):909-14.

View in: PubMed
Dutta A, Li J, Lu H, Akech J, Pratap J, Wang T, Zerlanko BJ, FitzGerald TJ, Jiang Z, Birbe R, Wixted J, Violette SM, Stein JL, Stein GS, Lian JB, Languino LR. Integrin av?6 promotes an osteolytic program in cancer cells by upregulating MMP2. Cancer Res. 2014 Mar 01; 74(5):1598-608.

View in: PubMed
Sato T, Tran TH, Peck AR, Liu C, Ertel A, Lin J, Neilson LM, Rui H. Global profiling of prolactin-modulated transcripts in breast cancer in vivo. Mol Cancer. 2013 Jun 12; 12:59.

View in: PubMed
Retting KN, Song B, Yoon BS, Lyons KM. BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development. 2009 Apr; 136(7):1093-104.

View in: PubMed
Kawaki H, Kubota S, Suzuki A, Lazar N, Yamada T, Matsumura T, Ohgawara T, Maeda T, Perbal B, Lyons KM, Takigawa M. Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage. J Bone Miner Res. 2008 Nov; 23(11):1751-64.

View in: PubMed
Cohen JC, Larson JE, Killeen E, Love D, Takemaru K. CFTR and Wnt/beta-catenin signaling in lung development. BMC Dev Biol. 2008 Jul 06; 8:70.

View in: PubMed
Matsen SL, Yeo CJ, Hruban RH, Choti MA. Hypercalcemia and pancreatic endocrine neoplasia with elevated PTH-rP: report of two new cases and subject review. J Gastrointest Surg. 2005 Feb; 9(2):270-9.

View in: PubMed
Yoon BS, Lyons KM. Multiple functions of BMPs in chondrogenesis. J Cell Biochem. 2004 Sep 01; 93(1):93-103.

View in: PubMed
Cingolani G, Bednenko J, Gillespie MT, Gerace L. Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta. Mol Cell. 2002 Dec; 10(6):1345-53.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement