"Receptors, Somatotropin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind GROWTH HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells. Activation of growth hormone receptors regulates amino acid transport through cell membranes, RNA translation to protein, DNA transcription, and protein and amino acid catabolism in many cell types. Many of these effects are mediated indirectly through stimulation of the release of somatomedins.
| Descriptor ID |
D011986
|
| MeSH Number(s) |
D12.776.543.750.750.555.770 D12.776.543.750.750.660.750
|
| Concept/Terms |
Receptors, Somatotropin- Receptors, Somatotropin
- Receptor, Growth Hormone
- Somatotropin Receptors
- Receptors, Growth Hormone
- Somatotropin Receptor
- Growth Hormone Receptor
- Hormone Receptor, Growth
- Growth Hormone Receptors
- Hormone Receptors, Growth
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Somatotropin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Somatotropin".
This graph shows the total number of publications written about "Receptors, Somatotropin" by people in this website by year, and whether "Receptors, Somatotropin" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Somatotropin" by people in Profiles.
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Xu J, Sun D, Jiang J, Deng L, Zhang Y, Yu H, Bahl D, Langenheim JF, Chen WY, Fuchs SY, Frank SJ. The role of prolactin receptor in GH signaling in breast cancer cells. Mol Endocrinol. 2013 Feb; 27(2):266-79.
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Xu J, Zhang Y, Berry PA, Jiang J, Lobie PE, Langenheim JF, Chen WY, Frank SJ. Growth hormone signaling in human T47D breast cancer cells: potential role for a growth hormone receptor-prolactin receptor complex. Mol Endocrinol. 2011 Apr; 25(4):597-610.
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Langenheim JF, Chen WY. Development of a novel ligand that activates JAK2/STAT5 signaling through a heterodimer of prolactin receptor and growth hormone receptor. J Recept Signal Transduct Res. 2009; 29(2):107-12.
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Yang N, Langenheim JF, Wang X, Jiang J, Chen WY, Frank SJ. Activation of growth hormone receptors by growth hormone and growth hormone antagonist dimers: insights into receptor triggering. Mol Endocrinol. 2008 Apr; 22(4):978-88.