"Receptors, Somatostatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind somatostatin and trigger intracellular changes which influence the behavior of cells. Somatostatin is a hypothalamic hormone, a pancreatic hormone, and a central and peripheral neurotransmitter. Activated somatostatin receptors on pituitary cells inhibit the release of growth hormone; those on endocrine and gastrointestinal cells regulate the absorption and utilization of nutrients; and those on neurons mediate somatostatin's role as a neurotransmitter.
Descriptor ID |
D017481
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MeSH Number(s) |
D12.776.543.750.695.850 D12.776.543.750.720.600.760 D12.776.543.750.750.555.760 D12.776.543.750.750.580.720 D12.776.543.750.750.700.800
|
Concept/Terms |
Receptors, Somatostatin- Receptors, Somatostatin
- Somatostatin Receptors
- SRIH Receptors
- Receptors, Somatotropin Release Inhibiting Hormone
- Receptors, SRIH
- Somatostatin Receptor
- Receptor, Somatostatin
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Somatostatin".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Somatostatin [D12.776.543.750.695.850]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Somatostatin [D12.776.543.750.720.600.760]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Somatostatin [D12.776.543.750.750.555.760]
- Receptors, Pancreatic Hormone [D12.776.543.750.750.580]
- Receptors, Somatostatin [D12.776.543.750.750.580.720]
- Receptors, Pituitary Hormone-Regulating Hormone [D12.776.543.750.750.700]
- Receptors, Somatostatin [D12.776.543.750.750.700.800]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Somatostatin".
This graph shows the total number of publications written about "Receptors, Somatostatin" by people in this website by year, and whether "Receptors, Somatostatin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
2002 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Somatostatin" by people in Profiles.
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Zhang T, Ahn K, Emerick B, Modarai SR, Opdenaker LM, Palazzo J, Schleiniger G, Fields JZ, Boman BM. APC mutations in human colon lead to decreased neuroendocrine maturation of ALDH+ stem cells that alters GLP-2 and SST feedback signaling: Clue to a link between WNT and retinoic acid signalling in colon cancer development. PLoS One. 2020; 15(10):e0239601.
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Leijon H, Remes S, Hagstr?m J, Louhimo J, M?enp?? H, Schalin-J?ntti C, Miettinen M, Haglund C, Arola J. Variable somatostatin receptor subtype expression in 151 primary pheochromocytomas and paragangliomas. Hum Pathol. 2019 04; 86:66-75.
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Modarai SR, Opdenaker LM, Viswanathan V, Fields JZ, Boman BM. Somatostatin signaling via SSTR1 contributes to the quiescence of colon cancer stem cells. BMC Cancer. 2016 12 07; 16(1):941.
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Hanaoka H, Tominaga H, Yamada K, Paudyal P, Iida Y, Watanabe S, Paudyal B, Higuchi T, Oriuchi N, Endo K. Evaluation of (64)Cu-labeled DOTA-D-Phe(1)-Tyr (3)-octreotide ((64)Cu-DOTA-TOC) for imaging somatostatin receptor-expressing tumors. Ann Nucl Med. 2009 Aug; 23(6):559-67.
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Kallal L, Benovic JL. Fluorescence microscopy techniques for the study of G protein-coupled receptor trafficking. Methods Enzymol. 2002; 343:492-506.
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Thakur ML, Kolan H, Li J, Wiaderkiewicz R, Pallela VR, Duggaraju R, Schally AV. Radiolabeled somatostatin analogs in prostate cancer. Nucl Med Biol. 1997 Jan; 24(1):105-13.