Receptors, Cholecystokinin

"Receptors, Cholecystokinin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell surface proteins that bind cholecystokinin (CCK) with high affinity and trigger intracellular changes influencing the behavior of cells. Cholecystokinin receptors are activated by GASTRIN as well as by CCK-4; CCK-8; and CCK-33. Activation of these receptors evokes secretion of AMYLASE by pancreatic acinar cells, acid and PEPSIN by stomach mucosal cells, and contraction of the PYLORUS and GALLBLADDER. The role of the widespread CCK receptors in the central nervous system is not well understood.

Descriptor ID	D011949
MeSH Number(s)	D12.776.543.750.695.170 D12.776.543.750.720.600.270 D12.776.543.750.750.360.200 D12.776.543.750.750.555.270
Concept/Terms	Receptors, Cholecystokinin Receptors, Cholecystokinin Receptors, Pancreozymin Cholecystokinin Receptor Receptor, Cholecystokinin Receptors, CCK CCK Receptor Receptor, CCK CCK Receptors Pancreozymin Receptors Cholecystokinin Receptors Receptors, Sincalide Receptors, Sincalide Sincalide Receptors Receptors, Caerulein Receptors, Caerulein Caerulein Receptors CCK-4 Receptors CCK-4 Receptors CCK 4 Receptors Receptors, CCK-4 Receptors, CCK 4 CCK-8 Receptors CCK-8 Receptors CCK 8 Receptors Cholecystokinin Octapeptide Receptors Octapeptide Receptors, Cholecystokinin Receptors, CCK-8 Receptors, CCK 8 Receptors, Cholecystokinin Octapeptide

Below are MeSH descriptors whose meaning is more general than "Receptors, Cholecystokinin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]
Receptors, Cholecystokinin [D12.776.543.750.695.170]
Receptors, Neurotransmitter [D12.776.543.750.720]
Receptors, Neuropeptide [D12.776.543.750.720.600]
Receptors, Cholecystokinin [D12.776.543.750.720.600.270]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Gastrointestinal Hormone [D12.776.543.750.750.360]
Receptors, Cholecystokinin [D12.776.543.750.750.360.200]
Receptors, Neuropeptide [D12.776.543.750.750.555]
Receptors, Cholecystokinin [D12.776.543.750.750.555.270]

Below are MeSH descriptors whose meaning is related to "Receptors, Cholecystokinin".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Cholecystokinin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Cholecystokinin" by people in this website by year, and whether "Receptors, Cholecystokinin" was a major or minor topic of these publications.

Bar chart showing 7 publications over 5 distinct years, with a maximum of 2 publications in 1996 and 1997

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	0	2
1997	1	1	2
1999	1	0	1
2000	1	0	1
2002	1	0	1

Below are the most recent publications written about "Receptors, Cholecystokinin" by people in Profiles.

Yen TW, Sandgren EP, Liggitt HD, Palmiter RD, Zhou W, Hinds TR, Grippo PJ, McDonald JM, Robinson LM, Bell RH. The gastrin receptor promotes pancreatic growth in transgenic mice. Pancreas. 2002 Mar; 24(2):121-9.

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Weinberg DS, So C, Ruggeri B, Biswas S, Barber M, Waldman S. Human cholecystokinin-A receptor is not an oncofetal protein. Dig Dis Sci. 2000 Mar; 45(3):538-43.

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Moonka R, Zhou W, Bell RH. Cholecystokinin-A receptor messenger RNA expression in human pancreatic cancer. J Gastrointest Surg. 1999 Mar-Apr; 3(2):134-40.

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Weinberg DS, Ruggeri B, Barber MT, Biswas S, Miknyocki S, Waldman SA. Cholecystokinin A and B receptors are differentially expressed in normal pancreas and pancreatic adenocarcinoma. J Clin Invest. 1997 Aug 01; 100(3):597-603.

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Obourn JD, Frame SR, Bell RH, Longnecker DS, Elliott GS, Cook JC. Mechanisms for the pancreatic oncogenic effects of the peroxisome proliferator Wyeth-14,643. Toxicol Appl Pharmacol. 1997 Aug; 145(2):425-36.

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Tsuei BJ, Povoski SP, Zhou W, Bell RH. Autoradiographic localization of cholecystokinin (CCK) receptor expression during the development of azaserine-induced rat pancreatic carcinoma. Pancreas. 1996 Nov; 13(4):401-6.

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Tsuei BJ, Povoski SP, Zhou W, Bell RH. Gastrin receptor expression during azaserine-induced rat pancreatic carcinogenesis. J Surg Res. 1996 Jun; 63(1):105-9.

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Zhou W, Povoski SP, Bell RH. Characterization of cholecystokinin receptors and messenger RNA expression in rat pancreas: evidence for expression of cholecystokinin-A receptors but not cholecystokinin-B (gastrin) receptors. J Surg Res. 1995 Mar; 58(3):281-9.

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Povoski SP, Zhou W, Longnecker DS, Jensen RT, Mantey SA, Bell RH. Stimulation of in vivo pancreatic growth in the rat is mediated specifically by way of cholecystokinin-A receptors. Gastroenterology. 1994 Oct; 107(4):1135-46.

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Zhou W, Povoski SP, Rosen NA, Longnecker DS, Bell RH. Characterization of cholecystokinin receptors in rat pancreas. Evidence for expression of CCK-A receptors but not CCK-B (gastrin) receptors. Ann N Y Acad Sci. 1994 Mar 23; 713:331-3.

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