RNA-Directed DNA Polymerase
"RNA-Directed DNA Polymerase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49.
| Descriptor ID |
D012194
|
| MeSH Number(s) |
D08.811.913.696.445.308.300.750 D12.776.964.775.375.750 D12.776.964.970.600.850.375.750
|
| Concept/Terms |
RNA-Directed DNA Polymerase- RNA-Directed DNA Polymerase
- RNA Directed DNA Polymerase
- Reverse Transcriptase
- RNA Transcriptase
- DNA Polymerase, RNA-Directed
- DNA Polymerase, RNA Directed
- RNA-Dependent DNA Polymerase
- DNA Polymerase, RNA-Dependent
- RNA Dependent DNA Polymerase
- Revertase
|
Below are MeSH descriptors whose meaning is more general than "RNA-Directed DNA Polymerase".
Below are MeSH descriptors whose meaning is more specific than "RNA-Directed DNA Polymerase".
This graph shows the total number of publications written about "RNA-Directed DNA Polymerase" by people in this website by year, and whether "RNA-Directed DNA Polymerase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "RNA-Directed DNA Polymerase" by people in Profiles.
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Jones SA, Murakami E, Delaney W, Furman P, Hu J. Noncompetitive inhibition of hepatitis B virus reverse transcriptase protein priming and DNA synthesis by the nucleoside analog clevudine. Antimicrob Agents Chemother. 2013 Sep; 57(9):4181-9.
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Tonini T, Claudio PP, Giordano A, Romano G. Retroviral and lentiviral vector titration by the analysis of the activity of viral reverse transcriptase. Methods Mol Biol. 2004; 285:155-7.
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Delaney WE, Yang H, Westland CE, Das K, Arnold E, Gibbs CS, Miller MD, Xiong S. The hepatitis B virus polymerase mutation rtV173L is selected during lamivudine therapy and enhances viral replication in vitro. J Virol. 2003 Nov; 77(21):11833-41.
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Smith-Kirwin SM, O'Connor DM, De Johnston J, Lancey ED, Hassink SG, Funanage VL. Leptin expression in human mammary epithelial cells and breast milk. J Clin Endocrinol Metab. 1998 May; 83(5):1810-3.
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Menko AS, Sokol F, Clark HF, Tan KB. Structural and enzymatic characterization of viper C-type virus. Arch Virol. 1976; 50(1-2):125-35.