"DNA Polymerase III" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms but may be present in higher organisms. Use also for a more complex form of DNA polymerase III designated as DNA polymerase III* or pol III* which is 15 times more active biologically than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and 5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same template-primer dependence as pol II. EC 2.7.7.7.
| Descriptor ID |
D004258
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| MeSH Number(s) |
D08.811.913.696.445.308.300.235
|
| Concept/Terms |
DNA Polymerase III- DNA Polymerase III
- Polymerase III, DNA
- DNA Pol III
- DNA Polymerase delta
- Polymerase delta, DNA
- DNA-Dependent DNA Polymerase III
- DNA Dependent DNA Polymerase III
|
Below are MeSH descriptors whose meaning is more general than "DNA Polymerase III".
Below are MeSH descriptors whose meaning is more specific than "DNA Polymerase III".
This graph shows the total number of publications written about "DNA Polymerase III" by people in this website by year, and whether "DNA Polymerase III" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "DNA Polymerase III" by people in Profiles.
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Matsumoto Y, Brooks RC, Sverzhinsky A, Pascal JM, Tomkinson AE. Dynamic DNA-bound PCNA complexes co-ordinate Okazaki fragment synthesis, processing and ligation. J Mol Biol. 2020 12 04; 432(24):166698.
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Layer JV, Debaize L, Van Scoyk A, House NC, Brown AJ, Liu Y, Stevenson KE, Hemann M, Roberts SA, Price BD, Weinstock DM, Day TA. Polymerase d promotes chromosomal rearrangements and imprecise double-strand break repair. Proc Natl Acad Sci U S A. 2020 11 03; 117(44):27566-27577.
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Costantino L, Sotiriou SK, Rantala JK, Magin S, Mladenov E, Helleday T, Haber JE, Iliakis G, Kallioniemi OP, Halazonetis TD. Break-induced replication repair of damaged forks induces genomic duplications in human cells. Science. 2014 Jan 03; 343(6166):88-91.
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Pluciennik A, Burdett V, Lukianova O, O'Donnell M, Modrich P. Involvement of the beta clamp in methyl-directed mismatch repair in vitro. J Biol Chem. 2009 Nov 20; 284(47):32782-91.
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Mito E, Mokhnatkin JV, Steele MC, Buettner VL, Sommer SS, Manthey GM, Bailis AM. Mutagenic and recombinagenic responses to defective DNA polymerase delta are facilitated by the Rev1 protein in pol3-t mutants of Saccharomyces cerevisiae. Genetics. 2008 Aug; 179(4):1795-806.
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Zhuang Z, Johnson RE, Haracska L, Prakash L, Prakash S, Benkovic SJ. Regulation of polymerase exchange between Poleta and Poldelta by monoubiquitination of PCNA and the movement of DNA polymerase holoenzyme. Proc Natl Acad Sci U S A. 2008 Apr 08; 105(14):5361-6.
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Jayan GC, Cordelier P, Patel C, BouHamdan M, Johnson RP, Lisziewicz J, Pomerantz RJ, Strayer DS. SV40-derived vectors provide effective transgene expression and inhibition of HIV-1 using constitutive, conditional,and pol III promoters. Gene Ther. 2001 Jul; 8(13):1033-42.
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Walker RL, Anziano P, Meltzer PS. A PAC containing the human mitochondrial DNA polymerase gamma gene (POLG) maps to chromosome 15q25. Genomics. 1997 Mar 01; 40(2):376-8.
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Smith TW, Lippa CF, de Girolami U. Immunocytochemical study of ballooned neurons in cortical degeneration with neuronal achromasia. Clin Neuropathol. 1992 Jan-Feb; 11(1):28-35.