Thromboxanes

"Thromboxanes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Physiologically active compounds found in many organs of the body. They are formed in vivo from the prostaglandin endoperoxides and cause platelet aggregation, contraction of arteries, and other biological effects. Thromboxanes are important mediators of the actions of polyunsaturated fatty acids transformed by cyclooxygenase.

Descriptor ID	D013931
MeSH Number(s)	D10.251.355.255.100.825 D10.251.355.310.166.971
Concept/Terms	Thromboxanes Thromboxanes

Below are MeSH descriptors whose meaning is more general than "Thromboxanes".

Chemicals and Drugs [D]
Lipids [D10]
Fatty Acids [D10.251]
Fatty Acids, Unsaturated [D10.251.355]
Eicosanoids [D10.251.355.255]
Arachidonic Acids [D10.251.355.255.100]
Thromboxanes [D10.251.355.255.100.825]
Fatty Acids, Essential [D10.251.355.310]
Arachidonic Acids [D10.251.355.310.166]
Thromboxanes [D10.251.355.310.166.971]

Below are MeSH descriptors whose meaning is related to "Thromboxanes".

Below are MeSH descriptors whose meaning is more specific than "Thromboxanes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Thromboxanes" by people in this website by year, and whether "Thromboxanes" was a major or minor topic of these publications.

Bar chart showing 4 publications over 4 distinct years, with a maximum of 1 publications in 2019 and 2021 and 2023 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2019	0	1	1
2021	1	0	1
2023	0	1	1
2024	0	1	1

Below are the most recent publications written about "Thromboxanes" by people in Profiles.

Wurtzel JGT, Lazar S, Askari S, Zhao X, Severa J, Ayombil F, Michael JV, Camire RM, McKenzie SE, Stalker TJ, Ma P, Goldfinger LE. Plasma growth factors maintain constitutive translation in platelets to regulate reactivity and thrombotic potential. Blood Adv. 2024 03 26; 8(6):1550-1566.

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Larsen HJ, Byrne D, ?zpolat T, Chauhan A, Bailey SL, Rhoads N, Reed F, Stolla MC, Adili R, Holinstat M, Fu X, Stolla M. Loss of 12-Lipoxygenase Improves the Post-Transfusion Function of Stored Platelets. Arterioscler Thromb Vasc Biol. 2023 10; 43(10):1990-2007.

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Kostyak JC, Mauri B, Patel A, Dangelmaier C, Reddy H, Kunapuli SP. Phosphorylation of protein kinase Cd Tyr311 positively regulates thromboxane generation in platelets. J Biol Chem. 2021 Jan-Jun; 296:100720.

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Patel A, Kostyak J, Dangelmaier C, Badolia R, Bhavanasi D, Aslan JE, Merali S, Kim S, Eble JA, Goldfinger L, Kunapuli S. ELMO1 deficiency enhances platelet function. Blood Adv. 2019 02 26; 3(4):575-587.

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Rocca B, Ciabattoni G, Tartaglione R, Cortelazzo S, Barbui T, Patrono C, Landolfi R. Increased thromboxane biosynthesis in essential thrombocythemia. Thromb Haemost. 1995 Nov; 74(5):1225-30.

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Savage MP, Goldberg S, Macdonald RG, Bass TA, Margolis JR, Whitworth HB, Taussig AS, Vetrovec G, Cowley M, Bove AA, et al. Multi-Hospital Eastern Atlantic Restenosis Trial. II: A placebo-controlled trial of thromboxane blockade in the prevention of restenosis following coronary angioplasty. Am Heart J. 1991 Nov; 122(5):1239-44.

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Prosdocimi M, Finesso M, Gorio A, Languino LR, Del Maschio A, Castagnoli MN, De Gaetano G, Dejana E. Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog. Am J Physiol. 1985 Apr; 248(4 Pt 2):H493-9.

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Prosdocimi M, Tessari F, Finesso M, Gorio A, Dejana E, Languino LR, Del Maschio A, de Gaetano G. Prostacyclin and thromboxane levels during cardiac ischemia in dogs. Adv Prostaglandin Thromboxane Leukot Res. 1985; 13:93-6.

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Walinsky P, Smith JB, Lefer AM, Lebenthal M, Urban P, Greenspon A, Goldberg S. Thromboxane A2 in acute myocardial infarction. Am Heart J. 1984 Oct; 108(4 Pt 1):868-72.

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Vlasses PH, Ferguson RK, Smith JB, Rotmensch HH, Swanson BN. Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients. Prostaglandins Leukot Med. 1983 Jun; 11(2):143-50.

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